前列素E_1注射液联合中药治疗下肢动脉硬化闭塞症  

Effect of prostaglandin E_1 and traditional Chinese medicine on limb atherosclerosis obliterns

作　　者：王晓凤[1] 陈苏宁[1] 于飞[1] 李宏升[1] 

机构地区：[1]中国医科大学附属盛京医院,沈阳110004

出　　处：《实用药物与临床》2009年第6期399-400,共2页Practical Pharmacy and Clinical Remedies

摘　　要：目的观察中西医结合疗法,即中医辩证联合前列素E1治疗下肢动脉硬化闭塞症的临床疗效。方法将93例动脉硬化闭塞症的患者随机分成3组,对照组(A组)采用一般西医对症治疗,西药治疗组(B组)在上述治疗的基础上加用前列素E1,中西医结合治疗组(C组)在B组的基础上联合中医辩证治疗。观察比较三组的临床疗效及足背动脉的血流速度、血流峰值的差异。结果C组的临床疗效明显优于对照组(P<0.01)。而B组与对照组比较差异亦有统计学意义(P<0.05)。治疗组血流速度及血流峰值与对照组比较,差异有统计学意义(P<0.05,P<0.01)。结论中西医结合即中医辩证联合前列素E1治疗下肢动脉硬化闭塞症在改善患者临床疗效及下肢血流等方面具有优势。Objective To observe the clinical effect of traditional Chinese medicine combined with prostaglandine E on limb atherosclerosis obliterns.Methods Ninty-three cases were distributed randomly to three groups：group A was treated with western routine therapy,group B was treated with western routine therapy and prostaglandin E1 injection,group C also took western routine therapy and prostaglandin E1 injection combined with differentiation of TCM.The differences of therapeutic effects and the mean blood flow velocity and peak blood flow of three groups were compared.Results Therapeutic effects of group C were more obvious than those of the control group（P〈0.05）.Compared with group A,the mean blood flow velocity and peak blood flow of group B and C increased significantly（P〈0.05,P〈0.01 ）.Conclusion TCM combined with prostaglandin E1 shows great effects on improving limb blood flow and clinical therapy.

关 键 词：下肢动脉硬化闭塞 中医辩证 中药治疗 

分 类 号：R543[医药卫生—心血管疾病]