长托宁与东莨菪碱烧伤麻醉前用药对心率与体温的影响  

Effect of penehyclidine hydrochloride and scopolamine intravenous on burn patients’ heart rates and temperatures before burn anesthesia as premedication

作　　者：李景锋[1] 郭富祥[1] 

机构地区：[1]锦州市解放军第205医院麻醉科,辽宁锦州121001

出　　处：《实用药物与临床》2009年第6期450-451,共2页Practical Pharmacy and Clinical Remedies

摘　　要：目的比较烧伤手术麻醉前用长托宁(盐酸戊乙奎醚)、东莨菪碱对患者心率、体温的影响。方法30例烧伤患者,男22例,女8例,随机分为2组,长托宁组15例,入手术室后肌注长托宁0.5mg;东莨菪碱组15例,入手术室后肌注东莨菪碱0.3mg。观察并记录用药前、用药后15min、30min、45min患者的心率、体温情况。结果与用药前比较,长托宁组患者心率、体温变化不明显(P>0.05),东莨菪碱组患者于注射后心率及体温升高(P<0.05)。结论长托宁作为烧伤手术麻醉前用药,对患者的心率、体温无明显影响,优于东莨菪碱。Objective To investigate the effects of Penehyclidine Hydrochloride and Scopolamine Intravenous on burn patients’ heart rates and temperatures before burn anesthesia as premedication.Methods 30 hospitalized ASA Ⅰ-Ⅱburn patients were randomly divided into two groups,penehyclidine hydrochloride （Group Ⅰ,n=15） or scopolamine（Group Ⅱ,n=15） was infused intravenously as premedication.Results In Group Ⅰ,the patients’ heart rates and temperatures remain the normal degree after given penehyclidine hydrochloride （P〉0.05）.In Group Ⅱ,the patients’ heart rates and temperatures increased at 15、30、45 minutes（P〈0.05）.Conclusion Penehyclidine hydrochloride can safely be used as intravenous premedication,especially for burn patients.

关 键 词：烧伤 长托宁 东莨菪碱 

分 类 号：R614[医药卫生—麻醉学]