阿司匹林赖氨酸盐在临床镇痛中的作用(附474例报告)  

Effect of Aspirin-DL-Lysine for Abdominal Pain

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作  者:苏艳[1] 吴杰[1] 王萍[1] 

机构地区:[1]武汉市中心医院消化内科,湖北武汉430014

出  处:《医学新知》2009年第6期349-350,共2页New Medicine

摘  要:目的评价阿司匹林赖氨酸盐用于非外科性腹痛的临床疗效。方法474例均因急性腹痛就诊,随机分为2组,治疗组用阿司匹林赖氨酸盐0.9g,静脉滴注;对照组用阿托品0.5mg,肌肉注射。观察2组的镇痛效果和不良反应。结果(1)治疗组:急性胃肠炎组(43例)、肾绞痛组(33例)、胆绞痛组(39例)、肠粘连组(34例)、急性胰腺炎组(47例)和功能性腹痛组(45例)疼痛缓解有效率分别为90.7%、84.8%、89.7%、82.4%、87.2%和82.2%。除9例出现出汗外未发现其他不良反应。(2)对照组:急性胃肠炎组(41例)、肾绞痛组(28例)、胆绞痛组(32例)、肠粘连组(29例)、急性胰腺炎组(52例)和功能性腹痛组(51例)疼痛缓解有效率分别为78.0%、57.1%、62.5%、69.0%、61.5%和68.6%。比较2组疗效差异有显著性(P〈0.05)。结论阿司匹林赖氨酸盐是一种有效、适应性广且副作用少的止痛剂。Objective To evaluate the effect of Aspirin-DL-Lysine for abdominal pain in order to provide evidence for the clinical treatment. Methods 474 patients with abdominal pain (239 male and 235 female) were injected with Aspirin-DL-Lysine 0.9g i. v. drip. Results The result showed that the effective rates of acute gastroenteritis group (43 cases), renal colic group (33 cases), biliary colic group (39 cases) , abhesion of intestine group (34 cases) , acute pancreatitis group (47 cases) and functional abdominal pain group(45 cases) were 90.7% , 84.8 % , 89.7 % , 82.4 % , 87.2% and 82.2% , respectively. There were slight side effects with only 9 accompany sweating. Conclusion Aspirin-DL-Ly- sine is effective for abdominal pain with few concomitant symptom.

关 键 词:阿司匹林赖氨酸盐 腹痛 

分 类 号:R971.1[医药卫生—药品]

 

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