中药“球康”对柔嫩艾美球虫超微结构的影响  

Effect of Chinese medicine Qiukang preparation on ultrastructure of Eimeria tenella

作　　者：周作勇[1] 王芝英[1] 聂奎[2] 

机构地区：[1]西南大学荣昌校区动物医学系,重庆402460 [2]西南大学动物科技学院,重庆400716

出　　处：《中国兽医科学》2009年第12期1120-1123,共4页Chinese Veterinary Science

摘　　要：利用透射电镜对中药"球康"作用下柔嫩艾美球虫超微结构的变化进行了观察。结果发现,在"球康"作用下,球虫裂殖子形态结构发生明显变化,表现为哑铃形、畸形和不规则形状,裂殖子的顶体肿胀变圆;裂殖子外膜破损,外膜与细胞质分离,出现大的空腔。球虫微线消失,内部出现环状结构;线粒体内出现空泡和致密的电子团块;球虫死亡,完全失去超微结构,仅留下许多支链淀粉颗粒。推测中药"球康"抗球虫的作用机理可能是,通过破坏虫体结构的完整性,抑制虫体物质代谢及能量代谢等生理机能,从而杀死球虫或者抑制球虫的生长和繁殖。The ultrastructures of Eimeria tenella in chic.kens treated by Chinese medicine Qiukang preparation were observed by a transmission electron microscope. Ultrastructural degeneration was characterized by cytoplasmic vacuolization, malformation and damage of cell membrane, vacuolization and condensing electron clump within the microneme, deformation of apicle, and in some cases, a complete loss of parasite ultrastructural organization. The results indicated that Qiukang led the ultrastructure of E. tenella to change,resulted in the death of merozoites or attenuation of the invading ability,inhibited the substance and energy metabolism,and killed E. tenella or inhibited the growth of E. tenella.

关 键 词：中药“球康” 柔嫩艾美球虫 超微结构 

分 类 号：S852.723[农业科学—基础兽医学]