胃肠康胶囊质量标准研究  

Study on Quality Standard for Weichangkang Capsules

作　　者：宗凯[1] 熊苗苗[1] 谢委[1] 汪秋兰[1] 

机构地区：[1]华中科技大学同济医学院附属同济医院药学部,武汉430030

出　　处：《医药导报》2010年第1期92-94,共3页Herald of Medicine

摘　　要：目的建立胃肠康胶囊的质量标准。方法采用薄层色谱(TLC)法对方中粉葛进行定性鉴别;采用高效液相色谱(HPLC)法测定了方中君药厚朴中厚朴酚与和厚朴酚的总含量。结果薄层鉴别专属性强;厚朴酚在0.0949～1.4232μg范围内、和厚朴酚在0.0402～0.6024μg范围内,呈良好的线性关系。厚朴酚平均加样回收率为101.18%,RSD=1.08%;和厚朴酚的平均加样回收率为100.47%,RSD=1.89%。结论该法快速、简便、准确、重现性好,可用于控制胃肠康胶囊的质量。Objective To establish the quality standard for weichangkang capsules. Methods Radix Puerariae in this medicine were identified by TLC. The total contents of maguolol and honokiol were determined by HPLC. Results The qualitative identification with TLC was specific. The methodological study showed a good linear relationship at rang of 0. 094 9 - 1.423 2 μg, 0.040 2 -0.602 4 μg. The average recover of magnolol was 101.18% （RSD = 1.08% ） , the average recover of honokiol was 100.47% （RSD = 1.89% ）. Conclusion The methods are simple rapid accurate and reliable, and can be used for quality control of weichangkang capsules.

关 键 词：胃肠康胶囊 厚朴酚 和厚朴酚 色谱法 高效液相 

分 类 号：R286[医药卫生—中药学] R927.2[医药卫生—中医学]