不同配伍雷米芬太尼和丙泊酚用于人流术的观察  

Observation on Application of Different Combinations of Remifentanil and Propofol in Artificial Abortion

作　　者：李彦文[1] 欧阳文[1] 段开明[1] 

机构地区：[1]中南大学湘雅三医院麻醉科,湖南长沙410013

出　　处：《实用预防医学》2010年第1期84-85,共2页Practical Preventive Medicine

摘　　要：目的观察雷米芬太尼和丙泊酚的两种不同配伍用于人工流产术的麻醉效果、不良反应与苏醒质量。方法将56例自愿行无痛人流术的病人随机分为P组和R组,每组28例。P组:缓慢静脉注射1.5 mg/kg丙泊酚和0.5μg/kg雷米芬太尼,必要时追加丙泊酚。R组:缓慢静脉注射0.5 mg/kg丙泊酚和0.8μg/kg雷米芬太尼,必要时追加雷米芬太尼。监测BP、HR、SPO2、RR,记录麻醉诱导时间、手术时间、苏醒时间、离室时间以及不良反应,评估术中镇痛效果及镇静程度。结果术中镇静程度、苏醒时间、离室时间、恢复早期宫缩痛及头晕等差异有统计学意义(P<0.05)。结论两组术中镇痛效果都满意,但R组不良反应更少,苏醒更快且质量更高。Objective TO observe the anesthesia effect, side effects and recovery quality of different combinations of remifentanil and propofol during artificial abortion. Metheds Fifty- six patients undergoing artificial abortion were divided randomly into two groups （each n=28）. Group P received intravenous propofol 1.5 mg/kg plus remifentanil 0.5 μg/kg, and propofol supplied if necessary. Group R received intravenous propofol 0.5 mg/kg plus remifentanil 0.8 μg/kg, and remifentanil supplied if necessary. BP, HR, SPO2, and RR were monitored. Anesthesia induction time, operation time, recovery time, the time of leaving operation room and side effects were recorded. The analgesic effect and sedation grade were evaluated. Results There were statistically significant differences in the sedation grade, recovery time, the time of leaving operation room, pains of uterine contraction and dizziness in the early recovery period （P〈 0.05）. Conclusions The analgesic effect of the two groups is satisfactory, and group R has less side effects, shorter recovery time and better recovery quality.

关 键 词：镇痛 镇静 雷米芬太尼 丙泊酚 人工流产术 

分 类 号：R169.42[医药卫生—公共卫生与预防医学]