单卵患者体外受精与卵胞浆内单精子注射授精方式的比较  

Comparing in vitro fertilization and intracytoplasmic sperm injection in patients with single oocyte retrieval

作　　者：马龙[1] 蔡令波[1] 冯婷[1] 严正杰[1] 刘嘉茵[1] 

机构地区：[1]南京医科大学第一附属医院临床生殖医学中心,南京210029

出　　处：《生殖医学杂志》2009年第6期513-515,共3页Journal of Reproductive Medicine

基　　金：973项目(2007CB948103);863项目(2006AA02Z4A4)资助

摘　　要：目的探讨仅获得一枚卵子的患者行体外受精(IVF)或卵胞浆内单精子注射(ICSI)治疗后受精率及妊娠率的差别。方法通过对本中心133个仅获得一枚卵的IVF治疗周期临床指标的分析,调查IVF与ICSI不同授精方式处理后受精率和妊娠率的差别。结果76个获得一枚卵IVF周期与57个获得一枚卵ICSI周期受精率和妊娠率均无统计学差异(73.7%vs 82.5%,P>0.05;10.5%vs 14.0%,P>0.05);其中<38岁组受精率和妊娠率分别为(73.9%vs 83.3%,13.0%vs 23.3%),>38岁组受精率和妊娠率分别为(73.3%vs 81.5%,6.7%vs 3.7%),均无统计学差异(P>0.05)。结论对于仅获得一枚卵子进行IVF或ICSI授精方式,其受精率及妊娠率没有统计学差异。Objective： To compare the efficacy of intracytoplasmic sperm injection （ICSI） and in vitro fertilization （IVF） in patients with single oocyte retrieval. Methods： The data of 133 cycles, which were accomplished in our ART center, are analyzed retrospectively, in order to determine whether the fertilization rates and pregnancy rates （PRs） change in patients who underwent either ICSI cycles or IVF cycles that resulted in single oocyte retrieval. Results： 76 IVF cycles and 57 ICSI cycles produced similar fertilization rates （73.7 % vs 82.5%） and PRs （10.5% vs 14.0%） ,there was no significant difference （P〉0.05） ; In patients at 438 years old,IVF and ICSI produced similar fertilization rates（73.9 % vs 83.3%） （P〉0.05） and PRs （13.0% vs 23.3%） （P〉0.05）, in patients at 〉38 years old,IVF and ICSI also produced similar fertilization rates（73.3 % vs 81.5%） （P〉0.05）and PRs （6.7% vs 3.7%）（P〉0. 05）. Conclusions： There was no significant difference in the fertilization rates and PRs in the patients who underwent either ICSI cycles or IVF cycles that resulted in single oocyte retrieval.

关 键 词：体外受精 注射治疗 取卵 精子 周期循环 胞浆 ICSI 试管婴儿 

分 类 号：S823.34[农业科学—畜牧学] S858.31[农业科学—畜牧兽医]