肝硬化自发性细菌性腹膜炎感染菌种分析  

Study on strains isolated from spontaneous bacterial peritonitis in patients with liver cirrhosis

作　　者：宋薇[1] 李康怡 吕东霞[1] 司永仁 

机构地区：[1]沈阳市第六人民医院肝病科,110006

出　　处：《国际流行病学传染病学杂志》2009年第6期373-374,共2页International Journal of Epidemiology and Infectious Disease

摘　　要：目的了解辽宁地区肝硬化患者的腹水感染菌种分类。方法对1925例肝硬化患者抽取腹水，采用床头接种入血培养基，分析细菌菌种。结果腹水细菌培养阳性166例（8.62％），生长11种细菌，革兰阴性菌牛长占64．46％，其中大肠埃希菌占总构成比的53．01％。在腹水培养阳性的患者中，肝功能Child—Pugh C级患者的病死率为63．25％；结论本地区肝硬化患者自发性细菌性腹膜炎的感染菌种以革兰阴性菌为主，临床上应有针对使用抗生素。Objective To investigate the distribution of strains isolated from ascites specimens in patients with liver cirrhosis in Liaoning. Methods The specimens of ascites were cultured. The bacterial confirmatory were carried out. Results 166 strains were isolated from the specimens of ascites. The positive rate was 8.62 %, gram-negative bacteria accounted for 64.46%, Escherichia coli（ E. coli ）accounted the first（ 53.01% ）. In the patients of ascites positive, the mortality in patients with liver cirrhosis （Child-Pugh C）was 63.25 %. Conclusions Gram-negative bacteria is the main pathogenic bacteria isolated from ascites specimens of spontaneous bacterial peritonitis in patients with liver cirrhosis. The antimicrobial agents should be applied effectively in clinical work.

关 键 词：肝硬化 细菌 腹膜炎 

分 类 号：R446.5[医药卫生—诊断学] R575.2[医药卫生—临床医学]