抗乙肝病毒中草药的化学成分  

Chemical Constituents of Anti-HBV Chinese Herbs

作　　者：金龙飞[1] 冯晓红[1] 金呈之[2] 吴腊梅[1] 

机构地区：[1]中南民族大学化学与材料科学学院,武汉430074 [2]中南民族大学生命科学学院,武汉430074

出　　处：《中南民族大学学报（自然科学版）》2009年第4期58-62,共5页Journal of South-Central University for Nationalities：Natural Science Edition

基　　金：湖北省自然科学基金重点资助项目(2008CDA067);湖北省自然科学基金资助项目(2007ABA121)

摘　　要：确定了具有抗乙肝病毒活性的中草药品种65种,其中含可能活性成分共16种,即芳烃、酮类衍生物、脂环族羧酸、芳香族羧酸、酯、内酯、氰类衍生物、杂环衍生物、类胡萝卜素、蒽醌类、黄酮类、植物鞣质、生物碱、萜类、甾类和蛋白质,而16种中以黄酮类、萜类、甾类和生物碱类成分为多.推测的有效成分主要包括脂环族羧酸、芳香族羧酸、蒽醌类、黄酮类、植物鞣质、生物碱和蛋白质.分析结果可为研制抗乙肝病毒药物和相关临床药物的应用提供依据.There are 65 species of Chinese herbs with confirmed anti-HBV activityd,in which 16 probable active constituents are pointed out.They are arene,ketone derivatives,alicyclic carboxylic acid,aromatic carboxylic acid,ester,lactone,cyanide derivatives,heterocycle derivatives,carotenoids,anthraquinones,flavonoids,vegetable tannin,alkaloid,terpenoids,steroids and protein.Among them,the complexes of flavonoids,terpenoids,steroids and alkaloids are more abundant.Probable effective constituents mainly contain alicyclic carboxylic acid,aromatic carboxylic acids,anthraquinones,flavonoids,vegetable tannin,alkaloid and protein.Results of the analysis provide basis for the study of anti-HBV drugs and applincation to related clinical medicine.

关 键 词：抗乙型肝炎病毒 中草药 有效成分 化学分析 

分 类 号：R978.7[医药卫生—药品] R284.1[医药卫生—药学]