中药对腹膜孔调控作用的实验研究  

Experimendal Study on the regulation of the peritoneal stomata by using chinese materia medica

作　　者：李继承[1] 吕志连 石元和[1] 沈毅[1] 俞寿民 

机构地区：[1]浙江医科大学淋巴学研究室浙江省中医研究院

出　　处：《中国中医基础医学杂志》1998年第8期20-22,共3页JOURNAL OF BASIC CHINESE MEDICINE

基　　金：国家中医药管理局重点基金;浙江省中医管理局重点资助

摘　　要：应用中医中药治疗肝硬化腹水的药物，进行动物实验。通过扫描电镜和计算机联机的图像处理系统，对药物的腹膜孔调控和促腹水转归作用，作了观察和定量分析。结果发现，丹参和泽泻均有显著开大腹膜孔的功能（Ｐ＜０．０５），并使腹膜孔开放数目增加，分布密度明显增高（Ｐ＜０．０５）。茯苓和茯苓皮对腹膜孔的调控作用均不明显（Ｐ＞０．０５）。本文结果首次证实丹参和泽泻对腹膜孔有调控作用。根据腹膜孔对腹水的转归机制。おhe pharmcological regulation of the peritoneal stomata and the mechanism of accelerated ascites drainage were observed by using a computer image processing system attached to SEM and chinses materia medica which used to treat hepatocirrhosis with ascites.The results showed that the numbers,diameters and distributive density of the peritoneal stomata were significantly increased (P<005) in root of red rooted salvia group and oriental water plantain group.However,the effect of tuckahoe and tuckahoe peel was not obvious in comprison with control (P>005).It was first time to be proved the regulation of the peritoneal stomata by using root of red rooted salvia and oriental water plantain.According to the mechanism of the peritoneal stomata and ascites drainage,root of red rooted salvia and oriental water plantain exert an important action on ascites absorption.

关 键 词：腹膜孔 腹水转归 中药 肝硬化腹水 腹水 治疗 

分 类 号：R285.5[医药卫生—中药学] R259.752[医药卫生—中医学]