国产无醋酸碳酸氢盐血液透析的临床观察  

Clinical Observation or China-made Acetate-free Hemodialysis(AFHD)

作　　者：张昭馥[1] 董葆[1] 陈秋乐 刘殿军[1] 吴醒身[1] 李洪艳[1] 刘仙娥[1] 于黎力 

机构地区：[1]海军总医院肾内科 [2]北京四维医药科技研究所

出　　处：《海军总医院学报》1998年第2期146-150,181,共5页Journal of Naval General Hospital of PLA

摘　　要：目的:探讨国产无醋酸碳酸氢盐血液透析液的效果.方法:观察并比较了32例尿毒症患者分别使用醋酸盐(AHD),常规碳酸氢盐(BHD),无醋酸碳酸氢盐(AFHD)血透的近期疗效.结果:清除低分子毒素、纠正电解质酸碱失衡三组相同,改善低氧血症、细胞免疫及心肌协调性、减少肿瘤坏死因子α(TNE_α)及临床不良反应AFHD优于BHD组.结论:国产无醋酸碳酸氢盐血透液效果良好,可否替代常规透析有待进一步深入研究.Objetive: In order to investigate the effect of China-made acetate-free hemodialysis(AFHD). Methods: 32 hemodialysis patients were observed and compared, when acetatehemodialysis (AHD), bicarbonate hemodialysis (BHD). acetate-free hemodialysis (AFHD) wereused seperately. Results: There was no difference in clearing low molecular toxin and adjustingelectrolyte acid-base disturbance among three groups. Group of AFHD manifested more signifi-cante then that of BHD, in a spect of improving hypoxia, cellular immune function, and cardiacmuscular coordination. At the same time, AFHD group reduced TNFα and clinical sideaction.Conclusion: China-made AFHD manifested significant effect. Howevere it will be used instead ofBHD is further proved.

关 键 词：无醋酸碳酸氢盐 血液透析 细胞因子 

分 类 号：R459.5[医药卫生—治疗学]