鲍曼不动杆菌256株的临床分布及耐药性分析  

Analysis on distribution and drug resistance of 256 strains of Acinetobacter baumannii

作　　者：张世勇[1] 张国欢[1] 

机构地区：[1]重庆市涪陵中心医院检验科,重庆408000

出　　处：《临床和实验医学杂志》2010年第2期95-96,共2页Journal of Clinical and Experimental Medicine

摘　　要：目的了解临床标本中鲍曼不动杆菌的分布特征和耐药情况。方法采用回顾性方法统计分析256株鲍曼不动杆菌的标本来源、感染科室分布及耐药状况。结果鲍曼不动杆菌最常出现在痰液标本中,占有81.25%,其次是分泌物和血液;临床分布以重症监护病房(ICU)最多,其次是呼吸内科和脑外科;鲍曼不动杆菌耐药现象严重,对亚胺培南的耐药率达27.34%,对其他抗菌药物的耐药率均大于65%。结论鲍曼不动杆菌是医院感染中重要的条件致病菌,其对抗菌药物耐药率高,且多重耐药,临床要重视合理使用抗菌药物,减少多重耐药菌株的产生。Objective To understand the characteristics of distribution and drug resistance of Acinetobacter baumannii in clinical specimens. Methods A total of 256 strains of Acinetobacter baumannii＇were retrospectively analyzed according to source of specimens, infections in different departments and drug - resistance. Results Among specimens from which Acinetobacter baumannii was isolated, sputum accounted for 81.25%. Secondly they were isolated from secretion and blood samples. Aeinetobaeter baumannii was mainly distributed in intensive care unit （ICU）, next were department of respiration and department of neurosurgery. The drug resistance of Acinetobacter banmannii was serious. The drug resistance rate of Acinetobacter baumannii to imipenem was 27.34% and its resistance to other antimicrobial agents was more than 65%. Conclusion Acinetobacter baumannii is the major opportunistic pathogenic bacteria in nosocomial infection which shows high rate of resistance to routine antimicrobial agents and even multiple drug resistance with important clinical significance. Antimicrobial agents should be rationally used in order to decrease multi - drug resistance.

关 键 词：鲍曼不动杆菌 医院感染 耐药性 

分 类 号：R446.5[医药卫生—诊断学]