飞行员高血压药物治疗前后立位耐力和+Gz耐力观察  

Orthostatic and +Gz tolerance in hypertension pilots before and after drug treatment

作　　者：郑军[1] 刘成刚[2] 刘晶[1] 刘玉华[1] 付兆君[1] 崔丽[1] 徐蜀宣[1] 熊巍[1] 徐先荣[1] 

机构地区：[1]空军总医院空勤科,北京100142 [2]空军总医院临床检验中心,北京100142

出　　处：《军医进修学院学报》2010年第2期116-118,共3页Academic Journal of Pla Postgraduate Medical School

基　　金：空后卫生部"十一.五"计划课题(KW06Z01)~~

摘　　要：目的观察飞行员患高血压病及药物治疗后立位耐力和+Gz耐力的变化。方法选择10例患高血压病的歼(强)击机飞行员,平均年龄(36±6)岁,经临床检查未发现心脑血管并发症,在药物治疗前和服降血压药血压恢复正常后分别进行20min立位耐力试验和+Gz耐力试验。结果药物治疗前立位耐力试验显示,平卧位平均血压为(147±16/92±10)mmHg(1mmHg=0.133kPa),立位(150±18/99±12)mmHg,卧立位舒张压差异有统计学意义(P<0.01);1例立位耐力试验结果阳性,5例+Gz耐力未达到所飞机种要求。降压药物治疗后,平卧位血压(131±10/80±7)mmHg,立位(130±8/87±3)mmHg,较治疗前均明显下降(P<0.01,P<0.05),立位耐力试验均为阴性;3例+Gz耐力未能达到所飞机种要求。结论高血压病对立位耐力和+Gz耐力有不利影响;药物治疗后+Gz耐力改善与病情和用药种类、剂量有关。Objective To observe the changes of orthostatic and ＋G tolerance in hypertension pilots before and after drug treatment. Methods Orthostatic and centrifuge tests were performed for 20min in 10 selected hypertension fighter pilots （mean age 36 ± 6 years） with no complication of cardio-cerebral blood vessels confirmed by clinical examination before and after drug treatment. Results The orthostatic test showed that the mean blood pressure of fighter pilots was （147 ± 16/92 ± 10）mmHg and （150 ± 18/99 ± 12）mmHg in supine position and standing position, respectively, before drug treatment（P〈0.01）. The orthostatic test was positive in 1 pilot and ＋Gz tolerance did not meet the flying standards in 5 pilots. The mean blood pressure of fighter pilots was （131 ± 10/80 ± 7）mmHg and（130 ± 8/87 ± 3）mmHg in supine position and standing position, respectively, after treatment with hypertension-reducing drugs （P〈0.01, P〈0.05）, which was significantly lower than that before treatment. The orthostatic tolerance was negative in all pilots and the ＋Gz tolerance did not meet the flying standards in 3 pilots. Conclusion Hypertension has a negative effect on orthostatic and ＋Gz tolerance. Improvement in ＋Gz tolerance after drug treatment is correlated with the severity of disease and the used types and doses of hypertension-reducing drugs.

关 键 词：高血压 药物疗法 飞行员 立位耐力 正加速度 

分 类 号：R544.1[医药卫生—心血管疾病] R852.21[医药卫生—内科学]