高血糖对红细胞平均体积测定的影响  

Effect of hyperglycemia on MCV measurement

作　　者：林军[1] 李勇[1] 戈一峰[1] 孟泽[1] 

机构地区：[1]南京军区南京总医院全军医学检验中心

出　　处：《临床检验杂志》1998年第5期280-283,共4页Chinese Journal of Clinical Laboratory Science

摘　　要：本文着重讨论在高血糖时用ＣｏｕｌｔｅｒＪＴ－ＩＲ血细胞计数仪测定ＭＣＶ引起假性增高情况。用ＥＤＴＡ－Ｋ２抗凝，制备１０个不同葡萄糖浓度的抗凝血，按０．５、２．５、５．０、８．０ｈ四个时间用Ｃｏｕｌｔｅｒ计数仪测ＭＣＶ值，用日立７１５０自动生化分析仪测葡萄糖浓度。结果显示：无论在体内或体外，随着葡萄糖浓度的增高，都将导致ＭＣＶ值假性增高。当血糖浓度在９０ｍｍｏｌ／Ｌ或更高时，ＭＣＶ值呈显著增高趋势。同时检测血常规和生化，结果显示ＭＣＶ随葡萄糖浓度的改变而相应改变，呈正相关。另外，病人血糖浓度虽然不高（正常），而血尿素却较高。The false increase of MCV in hyperglycemia was discussed in this article. Different amount of glucose was added into EDTA K 2 blood and the concentration of glucose was measured on HITACHI 7150 Automated Biochemical Analyzer. MCV was determined with Coulter JT IR electronic cell counter at 0 5,2 5,5 0,8 0 h after addition of glucose. The result showed the positive relevance between MCV and glucose concentration. MCV was significantly increased when glucose concentration was more than 90 mmol/L. False increase of MCV was also observed in higher blood BU with absence of hyperglycemia.

关 键 词：高血糖症 红细胞 血细胞计数仪 平均体积 

分 类 号：R446.113[医药卫生—诊断学] R589.1[医药卫生—临床医学]