158例普外科医院感染病原菌与耐药分析  

Drug Resistance and Pathogens in General Surgery Department:Analysis of 158 Cases

作　　者：刘文方[1] 陈春球[1] 安毅[2] 姬舒荣[1] 范跃祖[1] 

机构地区：[1]同济大学附属同济医院普外科,上海200065 [2]同济大学附属同济医院医院感染管理科,上海200065

出　　处：《中华医院感染学杂志》2009年第24期3433-3435,共3页Chinese Journal of Nosocomiology

摘　　要：目的了解普外科病房医院感染主要病原菌及耐药性,为临床合理使用抗菌药物提供依据。方法对2006年6月-2008年10月普外科病房158例医院感染患者进行回顾性分析和总结。结果普外科医院感染部位依次为下呼吸道、胃肠道、泌尿系统和手术切口;感染的革兰阴性杆菌中,依次为大肠埃希菌（18.02%）,鲍氏不动杆菌（11.26%）,铜绿假单胞菌（7.66%）,肺炎克雷伯菌（4.50%）;革兰阳性球菌中,依次为金黄色葡萄球菌（21.62%）,屎肠球菌（5.86%）和粪肠球菌（3.15%）;革兰阴性杆菌中,亚胺培南敏感率最高58.82%-100.00%;阿米卡星除对鲍氏不动杆菌外,敏感率〉70.00%;头孢哌酮/舒巴坦除铜绿假单胞菌外,敏感率〉50.00%;革兰阳性球菌中,金黄色葡萄球菌和屎肠球菌对万古霉素的敏感率分别为100.00%和84.62%。结论了解普外科医院感染病原菌的分布及抗菌敏感性,对临床合理使用抗菌药物,预防与控制医院感染发挥有效作用。OBJECTIVE To understand the pathogens and their drugs resistance in general surgery department and provide rational suggestion of antibiotics use for clinic treatment.METHODS A total of 158 cases with nosocomial infection among the general surgery department inpatients from Jun 2006 to Oct 2008 were retrospectively analyzed and summarized.RESULTS The common nosocomial infection sites were the lower respiratory tract,gastrointestinal tract,urinary tract and surgical sites.The G-bacilli of nosocomial infections in turn were Escherichia coli（18.02%）,Acinetobacter baumannii（11.26%）,Pseudomonas aeruginosa（7.66%）,and Klebsiella pneumoniae（4.50%）.The main G＋cocci were Staphylococcus aureus（21.62%）,Enterococcus faecium（5.86%）and E.faecalis（3.15%）in turn.In G-bacilli,the sensitivity to imipenem was the highest from 58.82% to 100.00%.The sensitivity to amikacin were more than 70.00% except A.baumannii,and to sulbactam/cefoperazone were more than 50.00% except Pseudomonas aeruginosa.In G＋ cocci,the sensitivity to vancomycin of S.aureus and E.faecium was 100.00% and 84.62%.CONCLUSIONS Investigating the pathogens and their drug resistance in general surgery department is very important to prevent and control nosocomial infections.

关 键 词：医院感染 病原菌 耐药性 

分 类 号：R378[医药卫生—病原生物学]