高血压、糖尿病、血脂异常及代谢综合征与超重和肥胖关系  

Association of Hypertension,Diabetes,Dyslipidemia,and Metabolic Syndrome with Overweight/Obesity

作　　者：张雷[1] 崔红月[2] 刘爱萍[1] 王培玉[1] 

机构地区：[1]北京大学公共卫生学院社会医学与健康教育系,北京100191 [2]北京市海淀区疾病预防控制中心慢病科,北京100037

出　　处：《中国慢性病预防与控制》2009年第6期561-563,共3页Chinese Journal of Prevention and Control of Chronic Diseases

摘　　要：目的评估北京市农村居民体质指数(BMI)的分布,不同BMI居民高血压、糖尿病、血脂异常及代谢综合征患病率及其与超重和肥胖的关系。方法对随机抽取的20 655名18～76岁农村居民进行横断面调查,通过问卷调查、体格检查和实验室检查收集资料进行分析。结果北京市农村居民体重正常、超重和肥胖的年龄别标化率分别为68.1%,24.2%和7.7%。正常体重、超重、肥胖1～3级居民高血压患病率分别为14.4%,27.5%,34.8%,44.3%和50.7%,糖尿病患病率分别为2.9%,5.0%,6.4%,8.1%和11.2%。正常体重居民血脂异常患病率最低(13.8%),肥胖2级最高(35.1%)。正常体重居民代谢综合征患病率最低(5.6%),肥胖3级居民最高(15.1%)。超重和肥胖1～3级分别是正常体重患高血压危险的2.6、3.1、3.8和4.7倍,肥胖3级糖尿病(OR=4.5)和代谢综合征(OR=3.2)患病危险最高,肥胖2级血脂异常(OR=3.4)患病危险最高。结论高血压、糖尿病、血脂异常和代谢综合征患病率随超重和肥胖级别增加而升高,超重和肥胖是高血压、糖尿病、血脂异常及代谢综合征的独立危险因素。Objective To estimate the distribution of bodyweight classes, up-to-date prevalence of hypertension, diabetes, dyslipidemia, and metabolic syndrome by different body mass index in suburban area in Beijing, and the association between these obesity-related diseases with overweight/obesity. Method A cross-sectional survey in a representative sampte of 20 655 suburban residents aged 18-76 years was carried out in 2007. Overweight and obesity classes 1, 2, and 3 were defined as a body mass index of 25.0 to 29.9, 30.0 to 34.9, 35.0 to 39.9, and ≥40 kg/m^2, respectively. Results The age-adjusted standardized rates of normal-weight, overweight, and obesity was 68.1%, 24.2%, and 7.7% in suburban area in Beijing, respectively. Among people with normal bodyweight, overweight, and obese class 1 to class 3, the prevalent rates of hypertension was 14.4%, 27.5%, 34.8%, 44.3% and 50.7%, respectively; the prevalent rates of diabetes was 2.9%, 5.0%, 6.4%, 8.1% and 11.2%, respectively; the prevalence of dyslipidemia was lowest in normal bodyweight participants （13.8%）, and highest in obese class 2 individuals （35.1%） and the prevalence of MS was 5.6% in normal bodyweight participants and was highest in obese class 3 （15.1%）. With normal body weight as reference, the adjusted OR of hypertension for overweight, obese class 1 to class 3 was 2.6, 3.1, 3.8, and 4.7, respectively. With normal body weight as reference, the adjusted ORs of diabetes and MS both peaked in obese class 3, at 4.5 and 3.2, respectively. In addition, after multivariable adjustment, participants of obese class 2 had the highest OR at 3.4 with normal bodyweight individuals as the reference. Conclusion Overweight/obesity is an independent risk factor for hypertension, diabetes, dyslipidemia, and metabolic syndrome. These findings emphasize the urgent need to develop effective strategies for the prevention of overweight/ obesity, in order to reduce the risk of these obesity-related diseases.

关 键 词：高血压 糖尿病 血脂异常 代谢综合征 超重和肥胖 

分 类 号：R587.1[医药卫生—内分泌] R544.1[医药卫生—内科学]