等容舒张期应变率评价冠心病心肌功能及病变程度  

Isovolumic relaxation strain rate evaluation of myocardial function and the coronary stenosis extent in coronary heart disease

作　　者：周爱云[1] 骆永芳[1] 刘娟[1] 

机构地区：[1]南昌大学第一附属医院超声诊断科,江西南昌330006

出　　处：《中国医学影像技术》2009年第12期2240-2242,共3页Chinese Journal of Medical Imaging Technology

摘　　要：目的应用应变率成像技术定量评价冠心病患者局部心肌功能及心肌缺血程度。方法对34例冠状动脉造影阳性患者和35名健康志愿者行应变率成像检查,获取左心室前壁、前间隔各节段等容舒张期应变率（SRivr）。结果左冠状动脉前降支轻度狭窄组（〈50%）SRivr与正常对照组差异无统计学意义,未能获得应变率参数截值;中度狭窄组（50%-74%）的截值SRivr为-0.42 s-1（灵敏度84.85%,特异度80.36%）;重度狭窄（〉75%）的截值SRivr为-0.91 s-1（灵敏度91.07%,特异度89.91%）。结论SRivr可定量评价左冠状动脉前降支中度或重度狭窄,应变率成像可反映缺血心肌的病变程度。Objective To quantitatively analyze myocardial function and the degree of myocardial ischemia with strain rate imaging（SRI）.Methods SRI was performed in 34 patients with left anterior descending coronary artery disease diagnosed with coronary angiography and compared with 35 healthy volunteers.Isovolumic relaxation strain rates（SRivr） of anterior wall and anterior septal were measured.Results There was no significant cut-off value for LAD50%.A cut-off value of SRivr=-0.42 s-1（sensitivity 84.85%,specificity 80.36%） for LAD 50%—74% stenosis.A cut-off value of SRivr=-0.91 s-1（sensitivity 91.07%,specificity 89.91%） for LAD75% stenosis.Conclusion SRivr can quantitatively differentiate LAD 50%—74% or LAD75% stenosis.SRI can evaluate the coronary stenosis extent quantitatively.

关 键 词：等容舒张期应变率 冠状动脉疾病 心肌功能 

分 类 号：R541.4[医药卫生—心血管疾病] R540.45[医药卫生—内科学]