羟苄羟麻黄碱治疗先兆早产的临床观察  

Hydroxyl Hydroxyl Benzyl Ephedrine in Treatment of Threatened Premature

作　　者：吴玲[1] 毕海燕[1] 

机构地区：[1]云南省第二人民医院产科,云南昆明650021

出　　处：《中国现代医生》2010年第1期43-44,共2页China Modern Doctor

摘　　要：目的探讨羟苄羟麻黄碱治疗先兆早产的临床疗效。方法研究对象随机分为麻黄碱组和硫酸镁对照组(n=36),观察两组有效抑制宫缩的显效时间、延长孕期、累积用药时间和药物副反应。结果治疗组与对照组比较:宫缩抑制显效时间([2.12±0.52)hvs(6.73±0.91)h]、累积用药时间([8.03±1.27)dvs(13.07±3.38)d]、延长孕期时间([25.64±5.36)dvs(15.37±4.85)d]、早产发生率(11.1%vs36.1%),差异有显著性(P<0.05)。结论羟苄羟麻黄碱治疗先兆早产安全有效,是治疗先兆早产较理想的药物。Objective To investigate the chnical efficacy of hydroxyl benzyl ephedrine in the treatment of threatened premature. Methods Subjects were randomly divided into the treatment group and control group （n=36 ）. The markedly inhibited uterine contraction time, the extension of pregnancy,the cumulative medication time and drug toxicity were observed in the two groups. Results A comparison between treatment group and control group showed the onset time of the inhibited uterine contraction was（2.12 ± 0.52）h vs （6.73 ± 0.91 ）h,the cumulative medication time was（8.03 ± 1.27）d vs （ 13.07 ± 3.38）d,the extended pregnancy time was（25.64 ± 5.36）d vs （ 15.37 ± 4.85）d and the incidence of prematurity was 11.1% vs 36.1% （all P〈0.05）. Conclusion Hydroxyl hydroxyl benzyl ephedrine is effective and feasible in the treatment of threatened premature delivery.

关 键 词：先兆早产 羟苄羟麻黄碱 疗效评价 

分 类 号：R714.21[医药卫生—妇产科学]