犬细小病毒病的流行现状调查  

Epidemiological Investigation of Canine Parvovirus

作　　者：耿志贤[1] 时彦胜[1] 郑亚平[1] 邱旭方[1] 周晓丽[1] 孔德强[1] 

机构地区：[1]军事医学科学院实验动物中心动物医院,北京100071

出　　处：《中国畜牧兽医》2009年第11期135-137,共3页China Animal Husbandry & Veterinary Medicine

摘　　要：对犬细小病毒病流行现状进行调查,为本病的预防、诊断和治疗提供依据。用犬细小病毒抗原检测试剂盒对2008年门诊的具有腹泻、呕吐、粪便带血等体征的189只患犬作病原检测,对犬细小病毒阳性病例兼有发热、咳嗽体征的16例病犬同时作犬瘟热病毒抗原检测。结果犬细小病毒阳性病例共137只,发病年龄从1个月-15岁各年龄段均有分布,以6月龄以下幼龄动物发病较多,占65.7%。流行季节差异不大,以春季病例略多,占27.0%。犬细小病毒与犬瘟热病毒混合感染的有12例,占8.8%。对在疫苗接种免疫保护期内的4只患犬进行检测,3只犬细小病毒阳性。结论：①免疫力尚未建立是幼犬发病的主要原因;②不按规定的免疫程序对动物进行加强免疫是成年犬发病的主要原因;③在部分发病幼犬中存在犬细小病毒与犬瘟热病毒的混合感染;④老龄动物对免疫的应答能力下降可导致免疫失败。To provide the basis for the disease prevention,diagnosis and therapy,epidemiological investigation of canine parvovirus was carried out.189 stool samples of dogs suffered from diarrhea,vomiting,blood feces and other signs were detected for antigen with canine parvovirus detection kit during 2008.And 16 samples of canine parvovirus-positive cases combined with fever,cough signs were detected for canine distemper virus at the same time.The cases of canine parvovirus-positive was 137.Dogs aged from 1 month to 15- years old could be infected. There was a high incidence in 6 months-old and more young animals, accounting for 65.7 % ,little difference among four seasons during the year, slightly more cases in spring, accounting for 27.0%. Canine parvovirus and canine distemper virus were found at the same time in I2 cases, accounting for 8.8%. Three of four samples were appeared to be positive for canine parvovirus during the term of vaccination protection. Conclusions： （1）Immunity has not yet been established, which is the main cause in puppies. （2） Not in accordance with established procedures to strengthen the immunity of animals is the main cause in adult dogs. （3）There are a few puppies co infected with canine parvovir us and canine distemper virus. （4）Aging animals are in low level on the immune response,which can lead to immune failure.

关 键 词：犬细小病毒 流行现状 发病原因 

分 类 号：S858.292[农业科学—临床兽医学]