肺部球形病变64层CT灌注成像后处理技术稳定性的研究  

Stability of the Perfusion Imaging Postprocessing Technology for Pulmonary Spherical Lesions Using 64-slice CT

作　　者：张庆华[1,2] 胡春洪[1] 顾光官[2] 

机构地区：[1]苏州大学附属第一医院影像中心,江苏苏州215006 [2]无锡市中医医院放射科,江苏无锡214001

出　　处：《中国血液流变学杂志》2009年第4期655-658,687,共5页Chinese Journal of Hemorheology

摘　　要：目的通过相同和不同测量者对同一组原始数据行后处理测定灌注参数值，以评价肺部CT灌注成像（CT Perfusion Imaging，CTPI）后处理技术对灌注参数测量的稳定性。方法肺孤立性球形病变患者30例，男17例，女13例。利用64层CT随机配置的body perfusion软件，用cine模式进行数据采集，所得原始数据传至Syngo工作站，由两名经过CT灌注成像技术应用培训的测量者采用统一的技术方法分别行后处理，得到CTPI图并测量病变的BF、BV、PS、MTT灌注参数值；一个月后其中一名测量者再以同样的方法重新处理一次。结果（1）相同测量者间、不同测量者间各灌注参数测量值的均差都较小，两次（者）测量差值基本位于95％一致性界限内；（2）相同测量者间、不同测量者间各灌注参数测量值的组内相关系数均大于0．8。结论64层CTPI后处理技术对肺孤立性球形病变灌注参数的测量具有较高的稳定性，获得的参数（BE、BV、PS、MTT）可用于定量分析。Objective To evaluate the stability and reliability of perfusion parameters got via postprocessing techniques in 64-slice CT pulmonary perfusion.Methods Thirty patients （17 males and 13 females） with solitary pulmonary spherical lesions were performed with the body perfusion technique of 64-slice CT scanner.All raw data were postprocessed via Syngo workstation by two independent observers,trained to use the technology proficiently, to get the perfusion images and the parameters （BF, BV, PS,and MTT）.A month later, using the same technology, an observer of the two postprocessed the raw data again.Results （1）All the mean differences for inter- and intraobserver agreement were minor, most of the differences between inter- or intra-observer＇s measurements were within 95% limits of agreement. （2）All the intraclass correlation coefficients for inter-or intra：observer＇s measurements were above 0.8.Conclusion There is great stability for CT perfusion parameters measured via postprocessing techniques in 64-slice CT pulmonary perfusion,all parameters （BF, BV,PS,and MTT） can be used for quantitative analysis.

关 键 词：体层摄影术 计算机 灌注成像 后处理技术 肺肿瘤 

分 类 号：R814.42[医药卫生—影像医学与核医学]