氨酚羟考酮在癌痛治疗中的作用与优势  

Effects and superiority of oxycodone-acetaminophen(Tylox) in the cancer pain treatment

作　　者：罗健[1] 李倩[1] 

机构地区：[1]中国医学科学院北京协和医学院肿瘤医院内科,北京100021

出　　处：《中国新药杂志》2009年第24期2313-2315,共3页Chinese Journal of New Drugs

摘　　要：癌痛是癌症患者常见症状,癌痛的有效处理取决于对癌症特点、癌症治疗方法以及疼痛程度、类型、性质等的充分了解。癌痛需综合治疗。另外,疼痛处理与癌症治疗相互影响,而药物治疗是疼痛综合治疗中的主要手段。众多国内外文献提示氨酚羟考酮(泰勒宁)可适用于各种癌症引起的不同部位、不同性质、不同程度的急性、慢性疼痛,可用于剂量滴定、也可用于维持治疗,镇痛疗效好,起效快,不良反应少且轻微。总之,世界卫生组织癌痛三阶梯治疗中第二阶梯复方制剂如氨酚羟考酮在癌痛中的作用与地位值得肯定。Cancer pain is a common, feared, but treatable component of malignancy. However, to successfully relieve the cancer pain requires a good understanding of tumor behavior, cancer therapy, pain intensity,pain type and other properties. Pain management is an integral component of comprehensive cancer care. In addition, pain therapy can interfere with or enhance cancer therapy and vice versa, and pharmacological approach is the main arm of the muhi-modality treatment of cancer pain. Many studies show the compound capsule of oxycodone-acetaminophen （Tylox） has very good analgesic effects on mild, moderate and even severe cancer pain both in the dose titration and the analgesic maintenance. In addition, Tylox has rapid analgesic onset with few and slight adverse effects. In conclusion, among two-step compounds of WHO three-step analgesic ladder,Tylox provides a new and important choice for caner pain treatment.

关 键 词：氨酚羟考酮 癌症疼痛 综合治疗 药物治疗 

分 类 号：R979.1[医药卫生—药品]