海拔4300m地区高原居民红细胞压积与心缩间期的关系  

Relationship between Hematocrit (Hct) and Cardiac Systolic Time Intervals (STI) in Residents at 4300 m Altitude.

作　　者：王小珍[1] 吴天一[1] 陈秋红[1] 魏春英 赵国强 

机构地区：[1]青海省高原医学科学研究所,西宁810012

出　　处：《航天医学与医学工程》1998年第5期365-367,共3页Space Medicine & Medical Engineering

摘　　要：为探讨高原居民红细胞及其压积对心缩间期的影响 ,在海拔 43 0 0m地区用心阻抗图法和心机械图法对 1 1 3名不同红细胞压积者的左室收缩功能进行了检测。结果 :红细胞压积与每搏量、射血分数呈显著负相关 ,而与射血前期与射血时间比值呈显著正相关(P <0 .0 0 1 )。随着红细胞压积值的增高 ,受试者的射血前期延长、左室射血时间缩短 ,射血前期与射血时间比值增大 ,射血分数下降。高原红细胞增多症患者的每搏量、心排出量明显下降。结论 :红细胞及其压积的高低对心缩间期和心泵功能的影响较大 ,红细胞增多是引起高原人体心功能降低的重要因素之一。In order to study the relationship between Hct and cardiasc systolic time intervals (STI) in residents at high altitude,STI and cardiac function were determined by electrical impedance and carotid arteriogram in 113 subjects with different Hct at an altitude of 4300 m.There was a negative correlation between Hct and SV or EF (r=-0.841 and -0.628),respectively (P<0.001).With increase of Hct there were prolonged pre-ejection period (PEP),shortenad left ventricular ejection time (LVET),and increased PEP/LVET .SV,CO were lower in high altitude polycythemia (HAPC) than in the control (P<0.05).It demonstrated that there is a close relationship between STI and Hct,and excessive polycythemia is one of the important factors that cause decrease of cardiac function decreasing in high altitude residents.

关 键 词：高原缺氧 血细胞比容 心功能 心缩期 

分 类 号：R594.3[医药卫生—内科学]