血管内氧合器的研制及其仿生学特点  

Fabrication of the intravascular oxygenator and exploration of its bionical characteristics

作　　者：江朝光[1,2] 林刚[1,2] 李功宋[1,2] 周津 杨溥臣 

机构地区：[1]解放军总医院心血管外科 [2]天津纺织工学院膜分离工程研究所

出　　处：《军医进修学院学报》1998年第4期246-248,共3页Academic Journal of Pla Postgraduate Medical School

摘　　要：目的：探索血管内氧合器的氧合机制，改进氧合器的气体交换效率。方法：采用国产聚丙烯中空纤维，自行设计，研制出一种血管内氧合器。对氧合器进行了动物实验研究。结果：应用血管内氧合器后，能部分改善缺氧及高碳酸血症动物的动脉血气指标，提高动脉血氧分压４．０６ｋＰａ（Ｐ＜０．０１），降低动脉血二氧化碳分压１．９９ｋＰａ（Ｐ＞０．０５）。并从仿生学角度进行了分析。Objective:In order to study the oxygenation mechanism of intravascular oxygenator(IVOX) and improve its practical efficiency Methods:A new IVOX was fabricated using polypropylene hollow fiber membrane and its efficacy was chacked on 9 experimental dogs Results:In vivo experimental testing of IVOX, arterial blood gas was improved in acute hypoxic and hypercapnic dogs The IVOX could increase PaO 2 4 06 kPa( P <0 01),and decrease PaCO 2 1 99 kPa( P >0 05) Conclusion:The new form of IVOX seems to be sucessful in improving hypoxic and hypercapnia but it is nessesary to further improve its efficiency along with bionics

关 键 词：血管内氧合器 仿生学特点 研制 

分 类 号：Q811.1[生物学—生物工程] R457[医药卫生—治疗学]