附睾、睾丸精子卵浆内单精子注射治疗阻塞性无精症引起不育  

Epididymas sperm aspiration or testicular sperm extraction with intracytoplasmic sperm injection for obstructive azoospermia

作　　者：李满[1] 庄广伦[1] 李蓉[1] 邓春华[1] 王长希[1] 张敏芳[1] 李俐琳[1] 

机构地区：[1]中山医科大学附属第一医院生殖医学研究中心

出　　处：《中华泌尿外科杂志》1998年第10期625-628,共4页Chinese Journal of Urology

摘　　要：为评价附睾或睾丸精子卵浆内单精子注射（ＩＣＳＩ）治疗阻塞性无精症引起不育的疗效，对３１例无精子男性不育患者配偶进行超排卵治疗３７个周期，获卵当日从患者附睾取精，其中２４例获得活动精子，７例失败，改用钳取睾丸曲细精管从中分离精子以供ＩＣＳＩ。结果：共获卵４５３个，附睾、睾丸精子ＩＣＳＩ受精率分别为５５７％、６１７％，平均每周期移植胚胎３７个，总妊娠率每周期２９７％。结论：只要获得活动精子ＩＣＳＩ。cases (37 ICSI cycles) of obstructive azoospermic males under went open or percutaneous epididymas sperm aspiration,sperm being obtained in 24.The rest 7 cases failed and in these cases testicular sperm were extracted instead.ICSI had been done in all these patients,the fertilization rate of epididymas group and testicular group has been 55.7% and 61.7% respectively.All their wives had embryos transfered,the pregnancy rate of them being 30% and 28.6%.It was concluded:Infertility caused by obstructive azoospermia can be treated with ICSI using aspirated epididymas or extracted testicular sperm.

关 键 词：男性不育 人工授精 卵浆注射 附睾 精子 无精症 

分 类 号：R698.205[医药卫生—泌尿科学] R321－33[医药卫生—外科学]