山东省丝虫性乳糜尿流行病学调查  

Epidemiological survey of filarial chyluria patients in Shandong Province

作　　者：傅斌[1] 李文备[1] 盛奇[1] 陈锡欣[1] 邓绪礼[1] 

机构地区：[1]山东省寄生虫病研究所,山东济宁272133

出　　处：《中国热带医学》2010年第1期1-2,18,共3页China Tropical Medicine

摘　　要：目的了解山东省班氏丝虫病流行现状,对晚期病人发病机理和治疗情况作出估计,为开展晚期病人照料工作提供依据。方法通过整群随机抽样方法调查了4个前班氏丝虫病流行区和对照区人群的的丝虫病患病情况。结果调查原丝虫流行区四个县区(镇)共190038人,查出现症乳糜尿111例(0.06%),非现症乳糜尿246例(0.13%),合计357(0.19%);以荣城县桥头镇为对照区,调查32146名居民,未发现乳糜尿患者,而且走访胶东半岛(非丝虫流行)15个县(区)内约有1800万人口地区的医院、门诊,未发现乳糜尿患者,医务人员也未接诊过乳糜尿患者,山东省寄防所门诊三十多年诊治的数以万计的乳糜尿患者中无一来自非丝虫病流行区者,充分证明了山东省非丝虫性乳糜尿极为罕见,在调查中发现的乳糜尿患者均为丝虫性乳糜尿。结论各县患病率与丝虫病流行程度(微丝蚴阳性率)成正相关(r=0.968,P<0.01),平均117例微丝蚴阳性者中有1例发展为乳糜尿患者,患者多为不规律间歇发作,劳累、情绪变化和受凉为常见诱因。约90%病例集中在21～59岁之间,是严重危害人民身心健康和社会经济发展的疾病。防治期间及后期出现发病例数增加是防治有效的标志,可持续到有效控制后5～10年。Objective To understand the provalent status of Filariasis Baneroffi in Shandong Province,investigate the pathology and treamtent oucome as well as offer evidence for taking care of filarial cases at advanced stages. Methods There 4 counties previously prevalent with fiariasis were surveyed as study area with a population of 190 038 pople and a township in Rongcheng County was taken as control area with a population of 32 146 people by random sampling. Results There 190 038 people in 4 townships of 4 counties were surveyed and patients with filarial ehy]uria,357 cases were discovered including 111 positives during the survey and 246 negatives but proved by reliable evidence,with a total morbidity rate of 0.19% . While no case was detected in Rongcheng County in non-endemic area where 32 146 people were surveyed. No ehyluria case ever reported from 15 counties of non-endemic area of Shandong. Conclusion Non-filarial ehyluria is rare in Shandong, all cases are filarial and case rate is related with the positive rate of micro-filaria statistically, one in about 117 miero-filarial cases developes chyluria,90% of the eases aged from 21 years old to 59,with irregular relapse and mostly place a premium on hard work, emotional change and coldness. Filarial chyluria is still a hazard of public health and of social economy development, but do not worry about the phenomena of the increase of case number of chyluria during mass control program, it may last five to ten years after well controlled.

关 键 词：山东省 班氏丝虫病 慢性丝虫病 乳糜尿 流行病学调查 

分 类 号：R532.15[医药卫生—内科学]