南海驻岛官兵血液流变学及凝血分析的变化  

Study on Hemorheology and Coagulation Function in Soldiers from South China Sea Islands

作　　者：何俐勇[1] 樊龙中[1] 周赤龙[1] 张腊喜[1] 谭燮伦[1] 王萍[1] 纪英萍[1] 喻云梅[1] 

机构地区：[1]中国人民解放军422医院检验科,广东省湛江市524005

出　　处：《中华全科医学》2010年第1期100-100,120,共2页Chinese Journal of General Practice

摘　　要：目的探讨南海驻岛礁官兵守礁前后血液流变学、凝血功能、血细胞的变化,为守礁部队预防保健工作提供理论依据。方法对守礁官兵守礁前后及航海组血液流变学、凝血酶原时间(PT)、部分凝血活酶时间(APTT),纤维蛋白原(FIB)、D-二聚体(D-dimer)、血细胞进行检测。结果守礁后官兵血液流变学中全血低切黏度(low-shear blood vis-cosity)、全血中切黏度(shear whole blood viscosity)、全血高切黏度(high-shear blood viscosity)、红细胞容积(Hct)、红细胞变性指数(RBC deformation index)、红细胞聚集指数(RBC aggregation index)、红细胞沉降率(ESR)增高,血浆黏度降低与对照相比差异有统计学意义(P<0.01,0.05);凝血酶原时间、部分凝血活酶时间增高,纤维蛋白原、D-二聚体下降与对照组相比差异有统计学意义(P<0.01,0.05);血细胞分析中红细胞、血小板、血红蛋白、红细胞容积增高,红细胞平均体积体积下降,与对照组相比差异有统计学意义(P<0.01,P<0.05)。结论驻岛官兵守礁后血液流变学数值升高是血液浓缩、红细胞体积减小引起红细胞发生质和形态的改变所致。血浆黏度下降与血浆蛋白减少有关。驻礁官兵守礁后凝血酶原时间,部分凝血活酶时间延迟,纤维蛋白原降低,可能是食物结构改变、营养成分下降、新鲜食物少使维生素缺乏、加上微量元素发生变化等等使它们的合成减少而引起。Objective To study the changes of hemorheology,coagulation function and blood corpuscle of soldiers from south China sea islands before and after the 3 months of defense task,in hope of providing provide theoretical basis for the health care and prevention of diseases in soldiers. Methods The hemorheology indexes, prothrombin time （PT） , partial thromboplastin time （AFVF） fibrinogen（FIB） ,D-dimer and blood corpuscle of the control group（ 104 soldiers from all-around depot ship） and study group（ 158 soldiers from island reef） were determined. Results The whole blood viscosity at different shear rate, hematocrit （Hct） ,RBC deformation index,RBC aggregation index, erythrocyte sedimentation rate（ESR） were higher, but plasma viscosity was lower in the study group as compared to the control group（ （ P 〈 0. 01 or P 〈 0.05 ） ）. PT and APTT of the study group were higher, but FIB and D-dimer were lower as compared to the control group （ P 〈 0. 01 or P 〈 0.05 ）. For coagulation function, RBC, PLT, Hb and Hct increased, while mean corpuscular volume（MCV） decreased, the difference between the two groups had statistically significance（ P 〈 0. 01 or P 〈 0. 05 ）. Conclusion In the soldiers from South China Sea islands, the high level of hemorheology indexes is associated to hemoconcentration, and red blood cell morphological changes caused by volume decrease. The decline in plasma viscosity is associated to the reduction of plasma protein. The changes of PT,APTT and FIB may be related to the structural changes in diet, decline in nutrient composition,less fresh food, vitamin deficiency and trace uptaking.

关 键 词：南海驻岛官兵 血液流变学 凝血分析 血细胞分析 

分 类 号：R821[医药卫生—临床医学] R446.11