复方醋酸钠注射液细菌内毒素的检测研究  

Study on the method of bacterial endotoxin test for compound sodium acetate injection

作　　者：柳涌[1] 常珍[1] 

机构地区：[1]安徽省立医院

出　　处：《中国医院药学杂志》1998年第10期453-455,共3页Chinese Journal of Hospital Pharmacy

摘　　要：目的：建立复方醋酸钠注射液的细菌内毒素检查法。方法：根据中国药典１９９５版二部收载的细菌内毒素检查法的要求进行实验。结果：将复方醋酸钠注射液经２倍稀释后可排除干扰因素，用标示灵敏度为０．５ＥＵ·ｍｌ－１的鲎试剂检测细菌内毒素是有效的。Objective: To establish bacterial endotoxin test method for compound sodium acetate injection. Methods:according to the Chinese pharmacopeia(1995).Results:It could eliminate interfering to dilute the compound sodium acetate injection twice. It is efffective to detect bacterial endotoxins with tachypleus amebocytelysate (λ= 0.5 EU/ml).Conclusion: Bacterial endotoxins test can replace the pyrogen test for compound sodium acetate injection.

关 键 词：复方醋酸钠 注射液 细菌内毒素试验 

分 类 号：R927.12[医药卫生—药学]