蟾酥的镇痛活性成分  

Research on the Active Analgesic Component of Venenum Bufonis

作　　者：张薇[1] 刘玉兰[1] 徐从云 高峨 包文芳[1] 

机构地区：[1]沈阳药科大学中药系

出　　处：《沈阳药科大学学报》1998年第4期268-271,共4页Journal of Shenyang Pharmaceutical University

摘　　要：药效学实验结果表明：蟾酥镇痛的活性成分主要存在于氯仿提取物中．分离蟾酥的氯仿提取物得到了脂蟾毒配基等６种单体化合物．６种单体化合物均具有一定的镇痛作用．华蟾毒精和脂蟾毒配基有非常显著的镇痛作用；蟾毒灵镇痛作用较平稳；By the method of Silica Gel Colume Chromatography,six compounds were gained from the chloroform extract of Venenum Bufonis.The analgesic effects of the above six compounds were researched by the Methods of Woolfe Macdonald and Mice Torsion.

关 键 词：蟾酥 镇痛 蟾毒灵 脂蟾毒配基 华蟾毒精 

分 类 号：R971.1[医药卫生—药品] R914.1[医药卫生—药学]