我院泌尿感染致病菌分布及耐药率监测  

Distribution of Pathogenic Bacteria in Urinary Tract Infection and the Drug Resistance

作　　者：谢诚[1] 包建安[1] 周中心[1] 缪丽燕[1] 

机构地区：[1]苏州大学附属第一医院药剂科,苏州市215006

出　　处：《中国药房》2010年第2期135-136,共2页China Pharmacy

摘　　要：目的:了解我院泌尿系统感染常见致病菌的分布及耐药情况,为临床抗菌药物的合理使用提供依据。方法:回顾性抽取2008年1～10月我院泌尿外科住院病历,对中段尿培养及药敏试验结果进行统计,结合现阶段泌尿外科抗菌药物的使用情况进行分析。结果:革兰阴性菌仍是泌尿系统感染的主要致病菌,占总菌数的61.82%,其中大肠埃希菌占革兰阴性菌的58.82%;对亚胺培南、阿米卡星、头孢哌酮/舒巴坦和哌拉西林/他唑巴坦的耐药率较低,分别为8.82%、8.82%、11.76%和11.76%。结论:临床在治疗尿路感染时应根据药敏试验结果正确选择抗菌药物。OBJECTIVE： To analyze the distribution of the common pathogenic bacteria and drug resistance in urinary tract infection for clinical reference of rational use of antibacterials. METHODS： The medical records of patients hospitalized in urinary surgery in our hospital from Jan. to Oct. in 2008 were retrospectively collected for analyses of the results of mid-stream urine culture and antibiotic resistance, meanwhile, the current utilization of antibacterials in urinary surgery was analyzed. RESULTS： Gram negative bacilli were the major pathogenic bacteria in urinary tract infection （61.82%） , of which, escherichia coli represented 58.82%, and the resistant rates of the gram negative bacilli to imipenem, amikacin, cefoperazone/sulbactam and piperacillin/tazo- bactam were 8.82%, 8.82%, 11.76% and 11.76%, respectively. CONCLUSION： The antibiotics should be used rationally according to the result of susceptibility test in treating patients with urinary tract infection.

关 键 词：泌尿感染 中段尿培养 耐药性 抗菌药物 

分 类 号：R969.3[医药卫生—药理学] R95[医药卫生—药学]