祛淤生新法对药物流产后大鼠子宫蜕膜超微结构的影响  

Effect of Eliminating Blood Stasis to Promote Regeneration of Blood on Ultrastincture of Pregnancy Decidua after Medical Abortion in Rats

作　　者：于燕[1] 张云竹[2] 金富锐[3] 边晓燕[1] 吴效科[1] 侯丽辉[1] 

机构地区：[1]黑龙江中医药大学附属第一医院,黑龙江哈尔滨150040 [2]黑龙江中医药大学2006级硕士研究生,黑龙江哈尔滨150040 [3]大连大学附属中山医院,辽宁大连116001

出　　处：《时珍国医国药》2010年第1期58-59,共2页Lishizhen Medicine and Materia Medica Research

基　　金：黑龙江省自然科学基金(No.D200649);哈尔滨市科技创新人才研究专项资金项目(No.2006RFQXS106);黑龙江省教育厅科学技术研究项目(No.11521262)

摘　　要：目的探讨祛淤生新法的代表方剂生化止血饮对药物流产后大鼠子宫蜕膜超微结构的影响。方法40只受孕大鼠随机分为正常孕鼠组、模型组、益母草组、生化止血饮组,电镜下观察药物流产后大鼠子宫蜕膜超微结构。结果正常孕鼠组均可见体积较大的蜕膜细胞;模型组均可见蜕膜细胞体积减小,细胞核曲度增加;益母草组部分蜕膜细胞开始凋亡,核皱缩;生化止血饮组蜕膜细胞已经凋亡被吞噬,未见蜕膜细胞。结论生化止血饮可明显促进药流后大鼠子宫蜕膜细胞调亡脱落并加速子宫内膜修复。Objective To investigate the effect of Sheughuazhixueyin from Eliminating blood stasis to promote regeneration of blood on uhrastructures of pregnancy decidua after drug - induced abortion. Methods 40 rats were divided into normal pregnant group, model group, Yimucao group and Shenghuazhixueyin group,the ultrastructures of pregnancy decidua after drug -induced abortion was observed under electron microscope. Results Normal pregnant group had normal decidual cell with big volume; model group had decidual cell with volume reducing and the cell nucleus curvature was inreased; inYimu cao group partial decidual cell began to apoptosis, the nuclear shrinked; in Shenghuazhixueyin group, the pregnancy decidua cell underwent and was swallowed, and the decidual cell was not been observed. Conclusion Shenghuazhixue yin from eliminating blood stasis to promote regeneration of blood can promote the pregnancy decidua cell apoptosis obviously and accelerate the endometrium regeneration.

关 键 词：祛淤生新 电镜 生化止血饮 子宫蜕膜 超微结构 

分 类 号：R285.5[医药卫生—中药学]