伤寒临床变迁的分析探讨  

CHANGES OF CLINICAL MANIFESTATIONS IN TYPHOID FEVER——A CLINICAL ANALYSIS OF 158 CASES

作　　者：王瑞云[1] 屠聿修[1] 陈钟英[1] 

机构地区：[1]南京医学院第一附属医院传染科

出　　处：《南京医学院学报》1990年第3期232-234,共3页

摘　　要：对我院1987～1988年2年中住院治疗的50例,与1970～1979年收治的108例伤寒患者临床资料对比分析,发现近2年江苏省伤寒病具有发病率高,流行持续时间长,病程长,病情重,并发症多,复发率高,治疗困难等特点,通过噬菌体分型,发现近2年伤寒是以耐氯霉素的MI型为优势菌株■之故。强调了氟哌酸、氨基甙类抗生素治疗效果好。The clinical features of 158 cases of typhoid fever in two groups—108 cases in 1970-1979 and 50 cases in 1987-1988--were analyzed with regard to morbidity,persistence of the epidemic, length and severity of the illness,rate of recurrences and therapeutic responses.The survey disclosed that in the past two years(1987-1988),typhoid fever in Jiangsu presented following characteristics:high morbidity,lengthening of the epidemic,prolonged and protracted clinical course,severer symptoms,more complications,a higher rate of recurrences and refractoriness to treatment.Bacteriophage typing showed that the causative agent of the epidemic was predominantly chloramphenicol-resistant type M_1 typhoid bacillus.The authors strongy recommend the therapeutic effectiveness of norfloxain and amicacin.

关 键 词：伤寒 噬菌体分型 抗药性 氟哌酸 

分 类 号：R516.302[医药卫生—内科学]