人工关节松动的防治研究进展  

Research Progress on Preventing Prosthesis Loosening after Artificial Joint Replacement

作　　者：杨朝君[1] 张元和[1] 

机构地区：[1]辽宁医学院附属第一医院骨科,辽宁锦州121001

出　　处：《辽宁医学院学报》2009年第6期565-567,共3页Journal of Liaoning Medical University (LNMU) Bimonthly

摘　　要：感染性松动和假体远期无菌性松动是人工关节在临床上存在并需要解决的问题。大量科研及临床事实证明,假体产生微粒与溶骨是无法消除的,后者与假体松动关系密切。在一定条件下,术后关节感染与假体松动又是相互促进的,关节的摩擦和微动,必然会在假体周围形成界膜和微粒,这就为病原微生物的繁殖提供了条件;反之,关节周围的感染所造成的骨破坏,也是关节松动下沉的一个原因。因此预防感染和减少磨损颗粒的产生对于预防人工关节的松动延长人工关节使用寿命意义重大。本文就预防感染和减少磨损颗粒的产生作一综述。Infectious loosening and aseptic loosening are the problems of artificial joint in clinical which needs to be addressed. Lots of scientific researches and clinical facts have proved that the particles,which produced by prosthesis and the osteolysis that are closely related to the prosthesis loosening,can not be eliminate.Postoperative joint infection and prosthesis loosening are also mutually reinforcing under certain conditions.Joint friction and micromotion should inevitably form the biofilm and debris around the prosthesis, which will provide a breeding ground for the propagation of pathogenic microorganisms.On the contrary,the destruction of bone around the joint caused by infection is one of the reasons of joint sinking.Therefore,preventing infection and reducing the generation of wear debris are of great significance for preventing artificial joint from loosening and for extending the service life of artificial joint.This paper is a review of the progress on preventing infection and reducing the generation of wear debris.

关 键 词：人工关节 感染 磨损颗粒 预防 

分 类 号：R687.4[医药卫生—骨科学]