小儿安神补脑颗粒治疗小儿多发性抽动症60例临床研究  

The clinical research of Xiaoer Anshen Bunao Granular for children with Tourette's syndrome of 60 cases

作　　者：邱静宇[1] 刘岩[1] 

机构地区：[1]深圳市中医院,广东深圳518033

出　　处：《中医儿科杂志》2010年第1期33-36,共4页Journal of Pediatrics of Traditional Chinese Medicine

基　　金：深圳市科技局科研项目(200703254)

摘　　要：目的探讨小儿安神补脑颗粒治疗小儿多发性抽动症的临床疗效,为治疗本病提供新的中成药制剂。方法将符合诊断标准的100例患儿随机分为治疗组60例,对照组40例。治疗组采用小儿安神补脑颗粒进行治疗;对照组服用氟哌啶醇片进行治疗。两组均以3月为1个疗程,共治疗2个疗程。观察两组治疗前后抽动症状次数、频率、强度、复杂性、干扰、损害等分数变化,用耶鲁综合抽动严重程度量表进行评定。结果1.治疗组在运动性抽动、发声性抽动、治疗后总疗效等方面均优于对照组,两组比较差异有统计意义(P<0.05)。2.治疗组远期疗效好、不良反应少,与对照组比较差异有统计意义(P<0.05)。3.治疗组治疗病程1年以内的患儿疗效最佳。结论小儿安神补脑颗粒对多发性抽动症患儿有显著的治疗作用。Objective To study the clinical therapeutic effect of Xiaoer Anshen Bunao Granular for children with Tourette＇ s syndrome, to provide a new proprietary Chinese medicine prescrition. Methods 100 patients accorded with diagnostic criteria were randomly divided into treatment group and control group. The treatment group was treated with Xiaoer Anshen Bunao Granular, while the control group was given Haloperidol. 3 months was a course of treatment in 2 groups, and treated 2 courses. Before and after treatment, observed the number of tic symptoms, frequency, intensity, complexity, interference, damage, such as changes in scores, took Yale Comprehensive Assessment to evaluate the severity of tic. Results 1. The treatment group was superior to the control group in the motor tic, vocal tic, the total effects after treatment and so on, which had significant difference in 2 groups （ P 〈 0.05 ）. 2. The treatment group had better long-term effects and fewer adverse reaction than the control group （ P 〈 0.05 ）. 3. The therapeutic effect in children who the course of treatment was in 1 year was best. Conclusion Xiaoer Anshen Bunao Granular has obviously treatment effect for children with Tourette＇ s syndrome.

关 键 词：小儿安神补脑颗粒 多发性抽动症 临床研究 

分 类 号：R272.3[医药卫生—中医儿科学]