脐血胃动素水平与胎粪排出关系的研究  

Relationship between umbilical motilin level and meconium passage

作　　者：张碧云[1] 肖小敏[1] 王自能[1] 张畅斌[2] 闵玲[2] 李屹[2] 吕莉娟[2] 

机构地区：[1]暨南大学第一附属医院妇产科,广州市510630 [2]广东省妇幼保健院,广州市510010

出　　处：《实用医学杂志》2010年第1期44-46,共3页The Journal of Practical Medicine

基　　金：广东省卫生厅基金资助项目(编号:B2007021)

摘　　要：目的:研究脐血胃动素(Motilin,MTL)水平与胎粪排出的关系。方法:用酶免疫分析法检测并比较足月分娩羊水性状正常(B组,122例)及中重度羊水粪染(A组,62例)的新生儿脐血及其孕母外周血血浆MTL水平。结果:A组新生儿脐血MTL值(343.69±206.73)pmol/L高于B组(139.05±80.06)pmol/L,差异有显著性意义(P<0.01),而两组孕妇外周血的MTL值无统计学差异(P>0.05)。羊水中度和重度胎粪污染者的孕妇外周血及脐血的MTL差异均无显著性(P>0.05)。结论:脐血MTL水平升高可能与胎粪排出有关。Objective To investigate the relationship between motilin concentration of umbilical plasma or maternal peripheral blood, and the mechanism of meconium passage. Methods The motilin level of umbilical blood and maternal peripheral blood were studied in two groups, one included 62 moderate or severe meconium-stained liquor （MSL） cases （31 of moderate MSL, and 31 of severe MSL）, and the other included 122 cases delivery with clear liquor as the control group. Results Deliveries with MSL had a significant higher level of motilin in umbilical plasma than those with clear liquor [ （343.69 ± 206.73） pmol/L vs （139.05 ± 80.06 pmol/L）] （P 〈 0.01 ）. But no statistically significant changes were noted in the level of motilin in the maternal peripheral blood （P 〉 0.05 ）. Neither the level of motilin in umbilical plasma nor in the maternal peripheral blood were found different between the moderate MSL group and the severe MSL group （P 〉 0.05）. Conclusion Maybe a high level of motilin in umbilical plasma in term neonates is related to meconium passage.

关 键 词：胎粪吸入综合征 胎儿窘迫 脐血 胃动素 

分 类 号：R714.7[医药卫生—妇产科学]