甲状旁腺机能减退症10例临床分析  

Hypoparathyroidism of 10 cases and review of literature

作　　者：邹东方[1] 李冰[1] 廖建湘[1] 

机构地区：[1]深圳市儿童医院神经内科,广东深圳518026

出　　处：《中国实用儿科杂志》2010年第1期43-46,共4页Chinese Journal of Practical Pediatrics

摘　　要：目的提高对甲状旁腺机能减退症(HP)的认识,总结其诊断及治疗经验。方法对深圳市儿童医院2002年4月至2009年4月来诊的10例HP患儿临床资料进行回顾性分析。结果特发性甲状旁腺机能减退症(IHP)5例,假性甲状旁腺机能减退症(PHP)5例;全部病例均存在低血钙、高血磷(除1例血磷正常),IHP甲状旁腺激素(PTH)水平低下,PHP则PTH水平高;经补钙及维生素D治疗后,临床症状均消失,血生化基本恢复正常;婴儿期即诊断明确者,疗效好,无智力及认知功能障碍。结论对癫痫及反复手足搐搦者,应及时行血钙、血磷、血清PTH测定,并行头颅CT检查。用钙剂及维生素D可以控制症状。治疗期间应定期复查血钙、血磷及24h尿钙。Objective To improve the level of recognization, diagnosis and treatment of hypoparathyroidism. Methods The clinical data of 10 patients with hypoparathyroidism, diagnosed between April 2002 and April 2009 in Shenzhen Children＇s Hospital, was retrospectively analyzed. Results In the 5 cases of idiopathic hypoparathyroidism （ IHP ）, and the other 5 cases of pseudohypoparathyroidism （ PHP ）, the blood calcium decreased, while serum inorganic phosphorus increased（except one case was normal）. The PTH decreased in the cases of IHP, and increased in the cases of PHP. With the treatment of calcium and Vitamin D, the symptoms were controlled, and the blood biochemistry returned to normal. Those who were identified during babyhood aehieved good effect, without disturbances on mentality and cognition. Conclusion Patients, who have epilepsy or repeated tetany, should be detected blood calcium, phosphorus, PTH and brain CT. The treatment of calcium and Vitamin D can control the symptoms. The blood calcium, phosphorus and 24-hour urinary calcium should be checked during treatment.

关 键 词：甲状旁腺机能减退症 血钙 血磷 

分 类 号：R72[医药卫生—儿科]