机构地区:[1]中国医学科学院北京协和医学院阜外心血管病医院放射科,100037
出 处:《中华放射学杂志》2010年第1期48-52,共5页Chinese Journal of Radiology
摘 要:目的分析儿童先天性心脏病双源CT(DSCT)扫描对冠状动脉显示的效果。方法2名放射科医师分别对儿童先天性心脏病DSCT扫描的图像评分,按冠状动脉各分支成像效果评为1—4分,3分以上为成像质量较好,可以用于诊断。采用方差分析比较3个心率水平、3个年龄段下冠状动脉评分差异及4支冠状动脉分支间评分差异。采用多元线性回归分析比较各支冠状动脉评分与年龄、心率、管电压、管电流、螺距、对比剂总量、对比剂流率的关系。结果共评价72例患儿(平均1.5岁),71.2%(205/288)的冠状动脉分支图像质量较好,可以用于诊断。左主干(3.64±0.49)分、前降支(2.97±0.40)分、右冠状动脉(2.82±0.70)分、回旋支(2.76±0.73)分,各支评分依次降低而不完全相同(F=29.00,P〈0.01)。〈1岁组(2.80±0.65)分、≥1~3岁组(2.81±0.74)分、〉3—14岁组(3.58±0.52)分,各组评分依次升高而不完全相同(F=20.16,P〈0.01)。心率〈100次/min(bpm)组(3.54±0.56)分,100~150bpm组(2.86±0.70)分,〉150bpm组(2.81±0.63)分,各组评分依次降低而不完全相同(F=16.72,P〈0.01)。多元回归分析显示年龄(r=0.013,P〈0.01)和对比剂总量(r=0.292,P=0.011)与左主干评分呈正相关;年龄(r=0.509,P〈0.01)、管电压与前降支评分呈正相关(r=0.292,P〈0.01),心率与前降支评分呈负相关(r=-0.179,P〈0.05);年龄与回旋支评分呈负相关(r=0.063,P〈0.01);年龄、管电压与右冠状动脉评分呈正相关(r值分别为0.486、0.220,P值分别〈0.01、〈0.05)。结论DSCT能够清晰显示3岁以上或心率〈100bpm的先天性心脏病儿童的冠状动脉,限制DSCT成像效果的是患儿的基础心律和年龄。Objective To analyze the image quality of coronary arteries by dual-source computed tomography(DSCT) in children with congenital heart disease (CHD). Methods Image quality of coronary arteries were scored by two radiologists with an ordinal grading system. Score 3 or 4 was considered to be good image quality and diagnostic. Score differences among 3 groups of various baseline heart rate levels, 3 groups of various age levels and 4 coronary branches were analyzed by using ANOVA. Multiple linear regression analysis was used to test the effects of age, heart rate, tube voltage, tube current, pitch, contrast volume, contrast injection rate on the coronary image scores. Results A total of 72 consecutive patients were enrolled. 71.2% (205/288) of coronary artery branches was good enough for diagnosis. Image quality of left main coronary artery ( LM, score 3.64 ± 0.49 ) , left anterior descending ( LAD, score 2. 97 ± 0. 40 ) , right coronary artery ( RCA, score of 2. 82 ± 0. 70 ) , left circumflex ( LCX, score 2. 76 ± 0. 73 ) were in a descending order ( F = 29. 00, P 〈 0. 01 ). Image scores of age groups of 0-1 years old ( 2. 80 ± 0. 65 ), 〉1-3 years old (2. 81±0.74), 〉3-14 years old (3.58 +0.52) were in an ascending order (F= 20. 16 ,P 〈 0. 01 ). Image scores of heart rate groups of 〈 100 bpm (3.54 -+ 0. 56), 100-150 bpm (2. 86 - 0. 70) and 〉 150 bpm (2. 81 ±0. 63) were in a descending order (F = 16. 72,P 〈0. 01 ). Muhiple linear regression analysis demonstrated that multiple impact factors affected image quality of LM, LAD, LCX and RCA. Age ( r = 0. 013, P 〈 0. 01 ) and contrast volume ( r = 0. 292, P 〈 0. 01 ) had positive correlation with LM score. Age(r = 0. 509, P 〈 0. 01 ) and voltage ( r = 0. 292, P = 0. 011 ) had positive correlation with LAD score. Heart rate(r = - 0. 179, P 〈 0. 05 ) had negative correlation with LAD score. Age ( r = 0. 063, P 〈 0. 01 ) had negative correlation with LCX
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