Treatment of Non-alcoholic Fatty Liver Disease by Qianggan Capsule(强肝胶囊)  

作　　者：李笠 张小晋 蓝宇 许乐 张学智 王化虹 

机构地区：[1]Gastroenterology Department,Beijing Jishuitan Hospital [2]Beijing Hospital [3]The First Hospital Affiliated to Peking University

出　　处：《Chinese Journal of Integrative Medicine》2010年第1期23-27,共5页中国结合医学杂志（英文版）

摘　　要：Objective： To observe the therapeutic effect and safety of Qianggan Capsule （强肝胶囊, QGC） in treating non-alcoholic fatty liver disease （NAFLD）, using potyene phosphatidylcholine capsule （PPC） as a reference. Metheds： Eighty-eight patients with NAFLD were randomly assigned to two groups, 45 in the treatment group treated with QGC and 43 in the control group treated with PPC. The course of treatment tasted for 6 months. Changes in liver function, blood lipids, and iconographic indexes before and after treatment were observed, and clinical efficacy was evaluated. Results： In the treatment group, alanine aminotransferase （ALT） was towered significantly from 56.02 ± 32.59 lUlL before treatment to 38.27 ± 22.68 IU/L after treatment, and CT liver/spleen ratio significantly increased from 0.69± 0.18 to 0.91 ± 0.25, showing statistical significance （P〈0.05）; in contrast, the corresponding changes of the two indexes in the control group were 56.56 ±26.33 IU/L to 49.67 ± 26.22 IU/L, and 0.66± 0.20 to 0.75 ± 0.24, respectively, the pre-post treatment difference showing insignificant difference （P〉0.05）. No severe adverse reactions occurred during the whole treatment course. Conclusion： QGC is an effective and safe remedy for the treatment of NAFLD.Objective： To observe the therapeutic effect and safety of Qianggan Capsule （强肝胶囊, QGC） in treating non-alcoholic fatty liver disease （NAFLD）, using potyene phosphatidylcholine capsule （PPC） as a reference. Metheds： Eighty-eight patients with NAFLD were randomly assigned to two groups, 45 in the treatment group treated with QGC and 43 in the control group treated with PPC. The course of treatment tasted for 6 months. Changes in liver function, blood lipids, and iconographic indexes before and after treatment were observed, and clinical efficacy was evaluated. Results： In the treatment group, alanine aminotransferase （ALT） was towered significantly from 56.02 ± 32.59 lUlL before treatment to 38.27 ± 22.68 IU/L after treatment, and CT liver/spleen ratio significantly increased from 0.69± 0.18 to 0.91 ± 0.25, showing statistical significance （P〈0.05）; in contrast, the corresponding changes of the two indexes in the control group were 56.56 ±26.33 IU/L to 49.67 ± 26.22 IU/L, and 0.66± 0.20 to 0.75 ± 0.24, respectively, the pre-post treatment difference showing insignificant difference （P〉0.05）. No severe adverse reactions occurred during the whole treatment course. Conclusion： QGC is an effective and safe remedy for the treatment of NAFLD.

关 键 词：non-alcoholic fatty liver disease Chinese medicinal therapy Qianggan Capsule polyenephosphatidylcholine capsule 

分 类 号：R285[医药卫生—中药学]