正交试验法优选牛膝的提取工艺  

Optimizing extraction technology of Radix Achyranthis Bidentatae by orthogonal test

作　　者：程永杰[1] 杨兴鑫[1] 张艳利[1] 李晓妮[1] 

机构地区：[1]山西医科大学药学院,太原030001

出　　处：《山西医科大学学报》2010年第1期42-44,共3页Journal of Shanxi Medical University

基　　金：山西省科技攻关基金资助项目(2007031201-01)

摘　　要：目的优选牛膝的最佳提取工艺。方法以牛膝总皂苷含量为评价指标,采用正交试验法筛选牛膝的最佳工艺条件。结果牛膝的最佳提取工艺条件为药材10倍量80%的乙醇,提取3次,每次1h。结论优化的提取工艺科学、合理,可以作为牛膝的最佳提取工艺方法。Objective To optimize the extraction technology of Radix Achyranthis Bidentatae. Methods Orthogonal test was em- ployed for selecting the optimum of extraction technology with Achyranthis Bidentatae Saponins as the index. Results The optimal ex- traction technology of Radix Achyranthis Bidentatae was 80% alcohol with 10 times volume of drugs, and extraction time of 3 times with 1 h for each time. Conclusion The optimized extraction condition is reasonable and scientific for extracting Radix Achyranthis Bidentatae.

关 键 词：牛膝 牛膝总皂苷 提取工艺 正交试验 

分 类 号：TQ460.6[化学工程—制药化工]