三七通舒治疗急性特发性面神经麻痹的疗效分析  

Sanqi Tongshu Capsule for Acute Idiopathic Facial Paralysis:A Clinical Controlled Trial

作　　者：刘静[1,2] 吴景芬[1,2] 韦永胜[1,2] 

机构地区：[1]四川省医学科学院 [2]四川省人民医院神经内科,成都610072

出　　处：《中国循证医学杂志》2010年第1期30-32,共3页Chinese Journal of Evidence-based Medicine

摘　　要：目的探讨三七通舒对急性特发性面神经麻痹的疗效。方法将86例特发性面神经麻痹急性期(发病7天内)患者分为两组,对照组42例采用激素、B族维生素、抗病毒治疗以及针灸理疗等基础治疗,三七通舒组44例采用基础治疗+三七通舒治疗,疗程28天。采用House-Brackmann面神经功能分级评定及临床疗效指标判定。治疗前后行面神经电图(ENoG)检查。结果治疗前两组H-B面神经功能分级、患侧EnoG的潜伏期及振幅均具有可比性。治疗28天后,两组H-B评分比较差异有统计学意义(治疗组2.33±1.21vs对照组3.08±1.35,P<0.05);面神经电图显示治疗组患侧潜伏期(2.46±0.34)及振幅(189±67)均较对照组潜伏期(3.37±0.49)及振幅(131±52)有改善,两组差异有统计学意义(P<0.05);临床疗效指标比较显示两组总有效率分别为:治疗组95.45%,对照组80.95%,治疗组明显优于对照组,两组差异有统计学意义(P<0.05)。结论三七通舒胶囊联合激素、B族维生素、抗病毒、针灸及理疗等综合治疗对急性特发性面神经麻痹有效。Objective To evaluate the effect of PNS on Idiopathic facial palsy. Methods A total of 86 cases of acute idiopathic facial paralysis were randomly divided into the treatment group （PNS group, 44 cases）, and the control group （42 cases）. The basis of the two groups included hormone therapy, B vitamins, anti-viral treatment, as well as acupuncture and physical therapy, both in the incidence of 7 days to give the treatment. House-Brackmann facial nerve function classification and evaluation were used to determine clinical efficacy; ENoG line was tested before and after treatment. Results Before H-B classification of facial nerve function, EnoG side of the latency and amplitude in the two groups were comparable. At 28 days after treatment, H-B scores for the treatment group and the control group were （2.33 ± 1.21） and （3.08 ± 1.35）, respectively, and the two groups had significant differences （P〈0.05）; ENoG incubation period （2.46 ± 0.34） and amplitude （189 ± 67） of the treatment group were more than those of the control group; the incubation period （3.37 ± 0.49） and amplitude （131± 52） improved, and there were significant differences between the two groups （P〈0.05）. Comparison of efficacy of the two groups showed the total effective rate： 95.45% in the treatment group, 80.95% in the control group, and the efficacy of the treatment group was better than that of the control group （P〈0.05）. Conclusion Sanqi tongshu, B vitamins, anti-virus, such as the acupuncture and physical therapy for the treatment of acute idiopathic facial paralysis have significant effect.

关 键 词：急性特发性面神经麻痹 三七通舒胶囊 临床对照试验 House-Brackmann 面神经电图 

分 类 号：R277.7[医药卫生—中医学]