轮状病毒肠炎并心肌损害临床分析  

Clinical analysis of rotavirus enteritis complicating cardiac damage

作　　者：林惠泉[1] 蔡海明[1] 付思源[1] 

机构地区：[1]福建医科大学附属漳州市医院儿科,福建漳州363000

出　　处：《中国医药导报》2010年第2期25-26,共2页China Medical Herald

摘　　要：目的:探讨轮状病毒肠炎并心肌酶谱和肌钙蛋白改变的临床意义。方法:对135例腹泻患儿采用酶联免疫吸附法检测粪便轮状病毒抗原,并做心肌酶谱(AST、LDH、CK、CK-MB)和肌钙蛋白测定、心电图检查;对临床资料进行分析。结果:观察组(粪轮状病毒抗原阳性)与对照组(粪轮状病毒抗原阴性)心肌损害发生率比较,差异有统计学意义(P<0.05)。轮状病毒对心肌的损害主要表现为心电图和心肌酶谱的异常,其中窦性心动过速最多见,其次是ST-T波改变。结论:轮状病毒感染常合并心肌损害,出现心肌酶、肌钙蛋白和心电图改变,多属于潜在性和亚临床型心肌损害,在治疗轮状病毒性肠炎时应注意观察病情。Objective： To investigate the clinical significance of cardiac muscle-zymogram and troponin changes in rotavirus enteritis. Methods： Rotavirus antigens of 135 children with coprorrhea were detected by ELISA. Cardiac muscle- zymogram （AST, LDH, CK, CK-MB）, troponin and electrocardiography of all cases were also examined. The clinical datas were analyzed. Results： In the incidence of myocardial damage, experimental group which rotavirus antigens were positive com- pared with control group which rotavirus antigens were negative, there was a significantly difference （P〈0.05）. Myocardium damaged by rotavirus showed that cardiac muscle-zymogram and ectrokardiogram were often abnormal. The most common type of electrocardiographic abnormality was sinus tachycardiainclude, abnormality of ST-T was in the next place. Con- clusion： The rotavirus infection often complicated with cardiac damage which showed abnormality in the cardiac muscle- z＇：~ogram, troponin and electrocardiogram. The more common types of cardiac damage were sub-clinical and potential, so we must pay attention to the cardiac damage in rotavirus enteritis.

关 键 词：轮状病毒肠炎 心肌损害 心肌酶谱 肌钙蛋白 

分 类 号：R725.7[医药卫生—儿科]