增龄及肾小球滤过率下降对合肥市老年体检人群贫血患病率的影响  

Effects of aging and decreased glomerular filtration rate on the prevalence of anemia in elderly population receiving body check from urban area of Hefei, China

作　　者：王德光[1] 洪海鸥[2] 任伟[3] 黄珍珍[3] 倪力军[3] 胡世莲[2] 

机构地区：[1]安徽医科大学第二附属医院肾内科,合肥230601 [2]安徽省立医院体检中心 [3]安徽省立医院肾内科

出　　处：《中华内科杂志》2010年第1期28-31,共4页Chinese Journal of Internal Medicine

摘　　要：目的探讨增龄及肾功能下降对合肥市老年体检人群贫血患病率的影响。方法回顾性分析2005年1月-2007年12月在安徽省立医院体检中心体检的所有年龄大于60周岁的人群，进行贫血患病率调查，分析增龄、估算的肾小球滤过率（eGFR）下降与贫血患病率之间的关系。结果在资料完整的4547例老年体检者中，贫血患病率为4．40％（95％CI：3．83％～5．05％），其中男性为4．04％（95％CI：3．37％～4．84％），女性为5．04％（95％CI：4．05％～6．24％）。贫血患病率随年龄增加、eGFR降低而升高，差异均有统计学意义（P〈0．001）。多因素logistic回归分析发现，增龄、女性、eGFR降低的OR分别为2．507、1．758和1．741。结论在合肥市老年体检人群中，贫血患病率为4．40％；增龄及肾小球滤过率下降是贫血患病率增加的独立危险因素。Objective To investigate the effects of aging and the decreased glomerular filtration rate on the prevalence of anemia in elder receiving body check from urban area of Hefei, China. Methods A total of 4547 〉60 years subjects received healthy examination in Healthy Center of Anhui Provincial Hospital from January ：2005 to December 2007 were enrolled in this study. Anemia was defined as hemoglobin 〈 120 g/L in men or 〈 110 g/L in women. Results The prevalence 0f anemia in the subjects was 4. 40% （95% CI：3.83%-5.05% ） and significantly increased with the aging process and the decline of estimated giomerular filtration rate （ eGFR ）. With logistic analyses, increasing age, female, decreased eGFR were major risk factors for anemia. Conclusions The morbidity of anemia is 4.40% in old population receiving body check from urban area of Hefei, China. Aging and the decline of eGFR are the independent risk factors of anemia.

关 键 词：贫血 患病率 老年人 肾小球滤过率 流行病学 

分 类 号：R556[医药卫生—血液循环系统疾病]