胃间质瘤患者胃电活动的初步研究  

A Preliminary Study on Gastric Electrical Activity in Patients with Gastrointestinal Stromal Tumor

作　　者：俞清翔[1] 陈茉[1] 王邦茂[1] 唐方[2] 方维丽[1] 常毅湘[1] 

机构地区：[1]天津医科大学总医院消化科,300052 [2]天津医科大学总医院中医科

出　　处：《天津医药》2010年第1期23-25,共3页Tianjin Medical Journal

摘　　要：目的:分析描述胃间质瘤(GIST)患者的胃电活动特点,探讨GIST对胃电活动的影响。方法:运用多导胃电图检测27例胃GIST患者(GIST组)及30例健康志愿者(对照组)的餐前餐后胃电参数,并进行对比分析。结果:对照组餐后各导联较餐前均出现平均频率(MF)、平均幅值(MA)及正常慢波百分比(N%)增高,过缓频率百分比(B%)较餐前减低,差异有统计学意义(P<0.05或P<0.01),GIST组未出现相应的胃电图改变(P>0.05);GIST组各导联餐前MF、MA高于对照组,N%餐前1、3、4导及餐后各导联均低于对照组,过速频率百分比(T%)各导联餐前餐后均高于对照组,差异有统计学意义(P<0.01);GIST组与对照组患者胃动过速发生率分别为66.7%,3.3%,GIST组节律正常患者所占百分比低于对照组,差异有统计学意义(P<0.01)。结论:GIST患者存在餐前餐后胃电活动异常,异常胃电节律以胃动过速为主。Objects：To investigate the behavior of gastric electrical activity in patients with gastrointestinal stromal tumor（GIST） to identify the influences of GIST on the normal gastric electrical activity. Methods：The electrogastrogram （EGG） parameters of 27 patients with gastric GIST （GIST group） and 30 healthy volunteers （control group） were detected by the multichannel electrogastrogram and the data were analyzed. Results：The values of postprandial mean frequency （MF）,mean amplitude （MA） and the percentage of normal slow wave （N%） were increased,and the percentage of bradygastria （B%） was decreased than those of the fasting in control group （P〈0.05 or P〈0.01）. However,those postprandial parameter changes were not found in GIST group （〉P0.05）. Compared with control group,the fasting MF and MA increased,the fasting N% of lead 1,3,4 and postprandial N% decreased,both percentages of fasting and postprandial tachygastria （T%） increased in GIST group （P〈0.01）. The tachygastria incidence was significantly higher in GIST group than that of control （66.7% vs 3.3%,P〈0.05）. Conclusion：The gastric electrical activity was affected by the existence of GIST. The abnormal gastric electrical rhythm displayed mainly as tachygastria.

关 键 词：胃肠道间质肿瘤 肌电描记术 肌电复合波 移行 病例对照研究 禁食 饭后期间 

分 类 号：R333.2[医药卫生—人体生理学] R735.2[医药卫生—基础医学]