2-(2-氯乙氧基)乙醇的制备方法  

The Method of 2-(2-Chloroethoxy)ethanol's Product

作　　者：瞿军 陆文辉 张符 吴宏祥 蒲梓荣[2] 金林荣[2] 何佳佩[2] 高启楠[2] 

机构地区：[1]江苏省扬州市普林斯化工有限公司,江苏扬州225654 [2]浙江绍兴文理学院化学系,浙江绍兴312000

出　　处：《河北化工》2010年第1期24-25,共2页Hebei Chemical Industry

摘　　要：二-(2-羟乙基)醚(俗称二甘醇)在甲苯中与偏硼酸酐反应得到偏硼酸三-(2-羟乙氧基-1-基)乙酯,再经氯化亚砜处理得到偏硼酸三-(2-氯乙氧基-1-基)乙酯,最后水解得到目标产物2-(2-氯乙氧基)乙醇。该工艺原料易得、操作简便、条件温和,最后总收率(以二甘醇计)达到68.3%。Metaboric acid tri-2- （2-chloroethoxy）ethanate has been synthesized through chlorination with SOCl2 of Tri-2- （2-hydroxyethoxy）ethanate, which was obtained from diethylene glycol and metaboric anhydride using toluene as the solvent, with SOCl2. The product 2-（2-chloroethoxy）ethanol can be obtained from tri-2-（2-chloroethoxy）ethanate through hydrolyzation. Easily obtainment of the raw material, convenient operation and mild conditions have been observed in this method. The total yield（based on diethylene glycol） is 68.3%.

关 键 词：偏硼酸酐 二甘醇 2-(2-氯乙氧基)乙醇 偏硼酸三-(2-羟乙氧基-1-基)乙酯 

分 类 号：R971[医药卫生—药品]