圆锥石头花中的三萜皂苷(英文)  

Triterpenoid Saponins from the Roots of Gypsophila paniculata

作　　者：姚舜[1] 马丽[1] 罗建光[1] 汪俊松[1] 孔令义[1] 

机构地区：[1]中国药科大学天然药物化学教研室,南京210038

出　　处：《中国天然药物》2010年第1期28-33,共6页

基　　金：supported by the National Natural Science Foundation of China for Outstanding Young Scientists (No.30525032)~~

摘　　要：目的:研究圆锥石头花根中的化学成分。方法:用 75%乙醇回流提取,乙酸乙酯和正丁醇依次萃取,采用硅胶、Sephadex LH-20、Rp-C18柱色谱法和制备液相色谱等方法分离纯化,根据理化性质和光谱数据鉴定化合物的结构。结果:从圆锥石头花根中分离得到8个多糖三萜皂苷。结论:化合物1～8首次从该植物中分离得到。AIM： To investigate the chemical constituents of Gypsophila paniculata L. METHODS： Compounds were isolated by silica gel, Sephadex LH-20, RP-C18 column chromatography and preparative liquid chromatography. Their structures were elucidated by ESI-MS, NMR, and acid hydrolysis. RESULTS： Eight known triterpenoid saponins （1-8） were isolated and elucidated. CONCLUSION： All triterpenoid saponins have been obtained from the roots of Gypsophila paniculata for the first time.

关 键 词：圆锥石头花 石竹科 三萜皂苷 

分 类 号：R284.1[医药卫生—中药学]