地榆炭化学成分的研究(Ⅰ)  

Study on Chemical Constituents of Charred Radix Sanguisorbae(Ⅰ)

作　　者：夏红旻[1] 孙立立[2] 孙敬勇[1] 仲英[1] 

机构地区：[1]山东省医学科学院药物研究所山东省现代医用药物与技术重点实验室,山东济南250062 [2]山东省中医药研究院,山东济南250014

出　　处：《食品与药品》2010年第1期42-44,共3页Food and Drug

基　　金：国家自然科学基金资助项目(30772786)

摘　　要：目的研究地榆炭的化学成分。方法采用色谱技术分离纯化,通过理化常数和波谱分析鉴定化合物结构。结果从地榆炭中分离6种化合物,分别为3,3,’4’-O-三甲基逆没食子酸(Ⅰ),3-O-甲基没食子酸甲酯(Ⅱ),3β,19α-二羟基-乌索-12-烯-28-酸(Ⅲ),3β-羟基-乌索-11,13(18)-二烯-28-酸(Ⅳ),β-谷甾醇(Ⅴ),胡萝卜苷(Ⅵ)。结论化合物IV系首次从地榆中分离得到。Objective To study the chemical constituents of charred Radix Sanguisorbae. Methods The compounds were isolated and purified by Column Chromatography and their structures were identified on the basis of physicochemical properties and spectral analysis. Results Six compounds were isolated and their structures were identified as 3,3＇,4＇-O-trimethylellagic acid（Ⅰ）, methyl 3-O-methyl-gallate（Ⅱ）,3β,19α-dihydroxyurs-12-en-28-oic acid（Ⅲ）, 3β- hydroxyurs- 11,13（18）-dien-28-oic acid（Ⅳ）, β-sitosterol（Ⅴ）, daucosterol（Ⅵ）. Conclusion Compound Ⅳ was isolated from Sanguisorba officinalis L. for the first time.

关 键 词：地榆炭 化学成分 结构鉴定 

分 类 号：R282.71[医药卫生—中药学]