一氧化氮在心血管疾病中的作用  

The Effect of Nitric Oxide on Cardiovascular Disease

作　　者：李鹏[1] 冯毅[1] 

机构地区：[1]东南大学临床医学院,南京210009

出　　处：《医学综述》2010年第1期31-33,共3页Medical Recapitulate

摘　　要：一氧化氮(NO)是调节心血管系统功能的重要细胞信使分子。NO的抗血小板、调节血管张力等功能在心血管疾病,如冠心病、心力衰竭、动脉粥样硬化、血栓形成等的发生发展中起着重要作用。NO通过对内皮细胞及微环境的作用来实现对血管的保护作用。一氧化氮合酶的活性及基因多态性的改变都影响着心血管疾病的发生、发展。Nitric oxide（NO） is one of the important cellular messengers which regulate the function of cardiovascular system. NO has many considerable effects on cardiovascular disease, such as coronary be＇art disease,heart failure, hypertension,artherosclerosis and thrombosis,because of its function on platelet aggregation prevention and angiotasis modulation regulation. NO could protect vaseellum through its effect on endotheliocyte and microenvironment, The activity and gene polymorphism of nitric oxide synthase can change the development of the cardiovascular disease.

关 键 词：一氧化氮 心血管疾病 动脉粥样硬化 

分 类 号：R54[医药卫生—心血管疾病]