2000年结核病流行病学抽样调查中耐药病例影响因素分析  

Risk factor analysis of drug-resistant tuberculosis cases in nationwide random survey for the epidemiology of tuberculosis,2000

作　　者：陈诚[1] 孙谨芳[1] 么鸿雁[1] 

机构地区：[1]中国疾病预防控制中心结核病预防控制中心,北京100050

出　　处：《疾病监测》2009年第12期945-947,共3页Disease Surveillance

基　　金：科技部科研院所社会公益研究专项(No.2004DIB1J034)

摘　　要：目的了解耐药结核病的危险因素。方法根据2000年结核病流行病学抽样调查个案数据库资料,选取性别、年龄、病例分类、地区、卫V项目5个因素进行单因素logistic回归分析。结果影响耐药的因素分析中,初治病例分类为耐药结核病的保护因素(OR=0.337,95%CI:0.222～0.512)。继发耐药影响因素分析中,45～59岁年龄组为继发耐药结核病的保护因素(OR=0.385,95%CI:0.201～0.738)。结论耐药、初始耐药、继发耐药的发生是多因素联合作用的结果,而非单一因素导致耐药,提示今后进行耐药结核病防治干预措施制定时,要考虑多种影响因素,制定综合防治措施,从而有效降低耐药结核病疫情。Objective To identify the risk factors of drug-resistant tuberculosis. Methods Five variables, including sex, age, category, location and health V project, were extracted to perform the one-way analysis based on the data of the random survey for the epidemiology of tuberculosis in 2000. Results The risk factor analysis of drug-resistant tuberculosis revealed that the categorization of cases for initial treatment was a protective factor（ OR = 0. 337,95% CI： 0. 222 - 0.512）. For secondary drug-resistance, the 45 to 59-year-old age group was a protective factor （ OR = 0. 385, 95% CI：0. 201 - 0. 738 ）. Conclusion The combined effect of multiple factors, contributing to the occurrence of drugresistant tuberculosis, either primary or secondary drug resistance, should be taken into account to establish comprehensive control and prevention strategies to curb the incidence of drug-resistant tuberculosis.

关 键 词：结核 因素分析 药物耐受性 

分 类 号：R52[医药卫生—内科学]