痤疮患者皮肤屏障功能受损原因分析  

Analysis on causes of destruction of skin barrier function in people with acne

作　　者：王燕[1] 马琼[1] 段静娴[1] 孙素姣[1] 陈丽华[1] 

机构地区：[1]大理学院临床医学院医学美容科,云南大理671000

出　　处：《中国美容医学》2010年第1期79-81,共3页Chinese Journal of Aesthetic Medicine

摘　　要：目的:探讨痤疮患者皮肤屏障功能受损的局部原因。方法:采用回顾性病例对照研究,对46例皮肤屏障受损及48例皮肤屏障功能正常的痤疮患者以下因素进行分析:外用药物、外用不正规的祛痘化妆品、皮肤清洁情况、护肤品使用情况及皮损严重情况,并进行统计学处理。结果:外用不正规的祛痘化妆品、外用酒精配制的擦剂、使用过热的水洗脸、使用香皂、洁面乳、频繁去角质护理、不使用化妆水和润肤剂是痤疮患者皮肤屏障受损的危险因素,保湿润肤剂对皮肤屏障有保护作用,而祛痘润肤剂对皮肤屏障保护作用不明显。皮肤屏障受损者Ⅲ度痤疮发生较多。结论:使用不正规的痤疮外用药物和化妆品及不正确护理皮肤会导致痤疮患者皮肤屏障功能受损,屏障功能受损可加重痤疮炎症的发生。Objective The local causes of destruction of skin barrier function in people with acne were studied. Methods 94 cases of people with acne were retrospectively reviewed with case-control study,out of them there were 46 patients with impaired skin barrier function.We compared external drug and cosmetic between patients and control, and their habits of washing face,for example water temperature, cleansing supplies,and whether they used astringents and emollients. Results The case group used irregular cosmetic （they were advertised to heal ance fast） and tincture were significantly more than the control patients,and they were tendency to wash face with higher water temperatrue,use soap or cleansing milk frequently,exfoliate more than three times a week,they did not favarite to use astringents and emollients.Moisturing emollients had a effect of protecting skin barrier function,but acne emollients had no-obvious effect of protecting skin barrier function.There were more Ill degree acne patients in case group. Conclusions Irregular topical application of external drug and cosmetic,incorrect way of skin care can impair skin barrier function of people with acne.lnflammtion of acne would become seriuos if skin barrier function was impaired.

关 键 词：皮肤屏障功能 受损 痤疮 

分 类 号：R758.733[医药卫生—皮肤病学与性病学]