重复序列及异染色质化在植物性染色体重组抑制中的作用  

Role of repetitive sequence and heterochromatize in recombination suppression of plant sex chromosomes

作　　者：高武军[1] 谢璐[1] 卢靖雯[1] 邓传良[1] 卢龙斗[1] 

机构地区：[1]河南师范大学生命科学学院,新乡453007

出　　处：《遗传》2010年第1期25-30,共6页Hereditas（Beijing)

基　　金：国家自然科学基金项目(编号:30970211);河南省自然科学基金项目(编号:2006180014)资助

摘　　要：重组抑制是植物性染色体由常染色体进化而来的前提条件,性别决定位点区域发生的重组抑制使早期的性染色体发生了退化和分化。研究表明,重组抑制的产生和染色体上一系列行为的发生有着密切的关系,如重复序列的累积、异染色质化及DNA的甲基化。转座因子和卫星DNA等重复序列的累积使早期植物性染色体形态和分子结构发生了分化,同时还导致性染色体的异染色质化,抑制了性染色体间的重组的发生。文章综述了这一领域的进展,并对DNA甲基化在植物性染色体重组抑制形成过程中可能的作用进行了简要分析。Suppression of recombination is the prerequisite for plant sex chromosome evolution from a pair of autosomes. Recombination suppression around the locus controlling sex determination results in sex chromosome degeneration and differentiation. Important events such as repetitive sequence accumulation, heterochromatize, and DNA methylation have relation to recombination suppression. Accumulation of repetitive DNA sequence, including transposable elements and satellite DNA, leads to primitive sex chromosome differentiated on morphological and molecular structure, and also gives rise to chromosome heterochromatize, and thus recombination between sex chromosomes was suppressed. Here, we reviewed the advances in this field, meanwhile, the function of DNA methylation in recombination suppression was analyzed.

关 键 词：染色体 重组抑制 重复序列 异染色质化 DNA甲基化 

分 类 号：Q943[生物学—植物学]