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作 者:白伟[1] 黄付敏[1] 斯琴[1] 祖淑玉[1] 韩少梅[1] 徐成丽[1] 朱广瑾[1]
机构地区:[1]中国医学科学院基础医学研究所北京协和医学院基础学院,北京市100005
出 处:《中国动脉硬化杂志》2009年第11期950-953,共4页Chinese Journal of Arteriosclerosis
基 金:国家科技部基础性专项重大课题(2006FY300110)
摘 要:目的研究黑龙江省血脂异常人群的分布特点及相关因素的调查分析,为血脂异常的防治提供科学依据。方法抽取黑龙江省哈尔滨市、牡丹江市、海林市不同年龄和职业的城乡居民3 481人(年龄2085岁,男性1509人,女性1 972人),进行体质检查和问卷调查,并采集空腹静脉血进行检测。包括总胆固醇、甘油三酯、高密度脂蛋白胆固醇、低密度脂蛋白及血糖。根据诊断标准筛查出血脂异常人群。结果检出血脂异常1 681人,检出率为48.3%,男性检出率54.5%,女性检出率43.6%;除20岁、40岁、50岁年龄组的高总胆固醇血症和高低密度脂蛋白血症外,其余血脂异常发生率在不同年龄、不同性别间均有显著性差异;非条件Logistic回归分析显示,有统计学意义的血脂异常的危险因素有年龄(OR=1.771)、性别(OR=1.384)、体质指数(OR=1.666)、空腹血糖(OR=1.919)、饮酒(OR=1.277)、吸烟(OR=1.515)、舒张压(OR=1.529)、腰围(OR=1.283)及腰臀比(OR=1.858),而体育锻炼(OR=0.802)是血脂异常的保护因素。结论对居民血脂异常的预防及干预是十分必要的,采取控制体重、血压、戒烟戒酒、加强锻炼、科学饮食等关键性措施,对预防和降低血脂异常的患病率有积极作用。Aim To research the distribution of dyslipidemia population and related factors in Heilongjiang Province and provide a scientific basis for the prevention and treatment of dyslipidemia. Methods A population based investigation was carried out cross-sectionally in a sample of 3 481(1 509 men and 1 972 women,aged from 2085).Total cholesterol(TC),triglyceride(TG),high density lipoprotein cholesterol(HDLC),low density lipoprotein(LDL) and glucose were measured and according to the diagnostic criteria dyslipidemia population were screened. Results Serum lipids abnormalities were found in 1 681 persons,and the detection rate was 48.3%,54.5% for men,43.6% for women.In addition to 20,40,50 the age group of high TC and high LDL,the remaining incidence of dyslipidemia in different ages and genders were significantly different.By non-conditional Logistic regression analysis,the statistical significant risk factors for dyslipidemia were age(OR=1.771),gender(OR=1.384),body mass index(OR=1.666),glucose(OR=1.919),alcohol(OR=1.277),smoking(OR=1.515),DBP(OR=1.529),waist circumference(OR=1.283) and waist-hip ratio(OR=1.858),and physical exercise(OR=0.802) was protective factors of dyslipidemia. Conclusions It is very necessary to take measures to prevent dyslipidemia.Taking control of body weight and blood pressure,elimination of tobacco and alcohol,strengthening exercise,balanced diet and other key scientific measures are positive to reduce the prevalence of dyslipidemia.
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